挽救性冷冻治疗前列腺癌。
Salvage cryotherapy for prostate cancer.
机构信息
Urology Department Portuguese Institute of Oncology Coimbra.
出版信息
Arch Ital Urol Androl. 2024 Jan 8;95(4):11897. doi: 10.4081/aiua.2023.11897.
BACKGROUND
Most men diagnosed with prostate cancer will be candidates for active treatment and 20 to 50% of patients treated with organ preserving strategies recur within the prostate. Optimal treatment of recurrence is controversial. Prostate cryosurgery has been increasingly used as primary, recurrence and focal treatment for prostate cancer.
METHODS
We analysed 55 patients submitted to cryotherapy as salvage treatment after recurrence.
RESULTS
Study population presented with a mean age of 70.9 ± 6.2 years, mean initial PSA of 7.6 ng/ml and average prostate volume by ultrasound of 43.2 ± 14.7 grams. Mean follow-up was of 18.0 months. Biochemical free survival at one year of follow-up was of 85%.
CONCLUSIONS
Cryotherapy can be an effective and safe treatment for recurrence after primary curative treatment failure.
背景
大多数被诊断患有前列腺癌的男性将成为积极治疗的候选者，而 20%至 50%接受保留器官策略治疗的患者在前列腺内复发。复发的最佳治疗存在争议。前列腺冷冻手术已越来越多地被用作前列腺癌的主要治疗、复发治疗和局部治疗。
方法
我们分析了 55 例接受冷冻治疗作为复发后挽救治疗的患者。
结果
研究人群的平均年龄为 70.9 ± 6.2 岁，初始 PSA 平均值为 7.6ng/ml，超声测量的前列腺平均体积为 43.2 ± 14.7 克。平均随访时间为 18.0 个月。随访 1 年时的生化无复发生存率为 85%。
结论
冷冻治疗可作为初次根治性治疗失败后复发的有效且安全的治疗方法。
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