Zhu Longyin, Zhang Huhai, Fang Jia, Xiao Shuang, Xiong Fu, Deng Caixia, Yang Qin, Fu Chunxiao, Pan Qianguang, Zhao Hongwen
Department of Nephrology, the First Hospital Affiliated to Army Military Medical University (Southwest Hospital), Chongqing, 400038, People's Republic of China.
Department of Infectious Disease, the First Hospital Affiliated to Army Military Medical University (Southwest Hospital), Chongqing, 400038, People's Republic of China.
Int Med Case Rep J. 2024 Jan 3;17:1-7. doi: 10.2147/IMCRJ.S442535. eCollection 2024.
We report a fatal case of massive airway bleeding caused by pulmonary strongyloidiasis in a patient with a transplanted kidney.
A 47-year-old male, regularly taking immunosuppressants post-kidney transplant, visited our hospital with symptoms of abdominal bloating, nausea, and emesis persisting for three days. After hospitalization, he developed a cough, hemoptysis, and respiratory failure. Sputum analysis confirmed an infestation with Strongyloides stercoralis. Despite receiving albendazole therapy and bronchoscopic management for bronchial hemorrhage, the patient ultimately died due to acute respiratory and circulatory collapse triggered by severe airway bleeding.
Patients undergoing immunosuppressive therapy following kidney transplantation are at increased risk for disseminated strongyloidiasis. Consequently, infectious disease screening prior to transplantation, along with essential preventive pharmacotherapy, is of paramount importance.
我们报告一例肾移植患者因肺类圆线虫病导致大量气道出血的致命病例。
一名47岁男性,肾移植后定期服用免疫抑制剂,因腹胀、恶心和呕吐症状持续三天前来我院就诊。住院后,他出现咳嗽、咯血和呼吸衰竭。痰液分析证实感染粪类圆线虫。尽管接受了阿苯达唑治疗和针对支气管出血的支气管镜处理,但患者最终因严重气道出血引发的急性呼吸和循环衰竭死亡。
肾移植后接受免疫抑制治疗的患者发生播散性类圆线虫病的风险增加。因此,移植前的传染病筛查以及必要的预防性药物治疗至关重要。