Seidler Annika, Aßmann Anton, Torgerson Paul R, Sánchez-Andrade José Suárez, Bischofberger Andrea
Equine Hospital, Vetsuisse-Faculty, University of Zürich, 8057 Zürich, Switzerland.
Section of Veterinary Epidemiology, Vetsuisse-Faculty, University of Zürich, 8057 Zürich, Switzerland.
Animals (Basel). 2023 Dec 19;14(1):15. doi: 10.3390/ani14010015.
The objective of this study was to compare articular cartilage thickness observed in the different 2D and 3D sequences to the cartilage thickness of the equine stifle in cadavers to determine the accuracy of each sequence. The study was conducted as a blinded laboratory study using seven equine stifle specimens. The 2D (T2W TSE) and 3D (3D VIEW T2W HR, T2 3D mFFE, T1W VISTA SPAIR, 3D PDW SPAIR) 3-tesla MRI sequences of each stifle were obtained. Cartilage thickness was measured at 30 locations on MRI and on gross pathology. Thickness measurements were compared using a Bland-Altman plot and post hoc analysis tests. The 3D sequences were found to be generally more accurate than the 2D sequence ( < 0.001). The smallest difference to macroscopic measurements was observed in the 3D VIEW T2W HR and T1W VISTA SPAIR sequences with no statistical difference between each other. Knowing the accuracy of different sequences will improve the evaluation of equine cartilage and the early detection of cartilage pathologies. This would promote MRI as a noninvasive imaging modality for horses suffering from stifle lameness with no findings in conventional imaging methods. Furthermore, since 3D sequences seem to have better accuracy in depicting cartilage, they may replace 2D sequences, thereby shortening scanning times.
本研究的目的是比较在不同二维和三维序列中观察到的关节软骨厚度与马尸体中膝关节软骨厚度，以确定每个序列的准确性。该研究作为一项盲法实验室研究，使用了七个马膝关节标本。获取了每个膝关节的二维（T2W TSE）和三维（3D VIEW T2W HR、T2 3D mFFE、T1W VISTA SPAIR、3D PDW SPAIR）3特斯拉磁共振成像序列。在磁共振成像和大体病理学上的30个位置测量软骨厚度。使用Bland-Altman图和事后分析测试比较厚度测量值。发现三维序列通常比二维序列更准确（<0.001）。在3D VIEW T2W HR和T1W VISTA SPAIR序列中观察到与宏观测量的最小差异，两者之间无统计学差异。了解不同序列的准确性将改善对马软骨的评估以及软骨病变的早期检测。这将促进磁共振成像作为一种无创成像方式，用于患有膝关节跛行且传统成像方法无发现的马匹。此外，由于三维序列在描绘软骨方面似乎具有更好的准确性，它们可能会取代二维序列，从而缩短扫描时间。
