Lee Youngjae, Baek Wonyong, Cho Jiwoong, Oh Jeonghyun
Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University Hospital, Gwangju 61453, Republic of Korea.
Diagnostics (Basel). 2024 Jan 4;14(1):110. doi: 10.3390/diagnostics14010110.
The frequency of concurrent thyroid cancer in patients with primary hyperparathyroidism (pHPT) varies. While the pathological association between thyroid and parathyroid disorders is frequently noted, the co-occurrence of parathyroid adenoma and papillary thyroid cancer is exceptionally rare. Furthermore, an ectopic parathyroid adenoma in the retropharyngeal space is exceedingly rare. Therefore, anatomical variations through the utilization of relevant diagnostic tools play a crucial role in guiding decisions pertaining to clinical manifestations, diagnostic methods, surgical interventions, and operative strategies for parathyroid tumors. We present a case of a 51-year-old female patient with papillary thyroid carcinoma in the right thyroid lobe and an ectopic parathyroid adenoma in the retropharyngeal space confirmed through surgical intervention. The elevated preoperative levels of serum calcium and parathyroid hormone, along with low serum phosphate, returned to normal ranges after surgery. This case sheds light on the unusual occurrence of an ectopic parathyroid adenoma in the retropharyngeal region within a thyroid cancer patient, providing valuable insights into the realm of thyroid malignancies.
原发性甲状旁腺功能亢进症(pHPT)患者并发甲状腺癌的频率各不相同。虽然甲状腺疾病与甲状旁腺疾病之间的病理关联屡见不鲜,但甲状旁腺腺瘤与甲状腺乳头状癌同时出现的情况极为罕见。此外,咽后间隙的异位甲状旁腺腺瘤极其罕见。因此,借助相关诊断工具了解解剖变异,对于指导甲状旁腺肿瘤的临床表现、诊断方法、手术干预及手术策略的决策至关重要。我们报告一例51岁女性患者,经手术干预证实其右甲状腺叶患有甲状腺乳头状癌,且在咽后间隙存在异位甲状旁腺腺瘤。术前血清钙和甲状旁腺激素水平升高,同时血清磷酸盐水平降低,术后恢复至正常范围。该病例揭示了甲状腺癌患者咽后区域出现异位甲状旁腺腺瘤这一罕见情况,为甲状腺恶性肿瘤领域提供了宝贵的见解。