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髋部骨折手术后出院时恢复直接口服抗凝剂是否安全?一项回顾性研究。

Is It Safe to Resume Direct Oral Anticoagulants upon Discharge after Hip Fracture Surgery? A Retrospective Study.

作者信息

Katzir Alona, Fisher-Negev Tamar, Or Omer, Jammal Mahmoud, Mosheiff Ram, Weil Yoram A

机构信息

Department of Orthopedic Surgery, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Kalman Yaakov Man Street, Jerusalem 9112001, Israel.

出版信息

J Clin Med. 2023 Dec 19;13(1):17. doi: 10.3390/jcm13010017.

Abstract

This study aimed to examine the incidence rate of early reoperations following hip fracture surgery and determine the safety of resuming direct oral anticoagulants. Many orthopedic surgeons are reluctant to resume chronic anticoagulation therapy for patients after surgical intervention for hip fractures. One of the main reasons is the potential for reoperation in the case of surgical complications. We conducted a retrospective cohort study at an Academic Level I trauma center, reviewing the records of 425 geriatric patients (age > 60) who underwent hip fracture surgery between 2018 and 2020, including a subgroup treated with direct oral anticoagulants prior to hospitalization. The study assessed the incidence rate of complications requiring early reoperation. Out of the 425 patients, only nine (2%) required reoperation within a month after discharge, with two (0.5%) on chronic anticoagulation therapy. None of the reoperations were urgent, and all were performed at least 24 h after re-admission. The findings revealed a very low incidence rate of reoperations in patients who underwent hip fracture surgery, with no reoperations performed within 24 h of re-admission. Consequently, we believe that resuming chronic direct oral anticoagulants is a safe and effective approach when discharging patients after hip fracture surgery.

摘要

本研究旨在调查髋部骨折手术后早期再次手术的发生率,并确定恢复直接口服抗凝剂的安全性。许多骨科医生不愿在髋部骨折手术干预后为患者恢复长期抗凝治疗。主要原因之一是手术并发症时可能需要再次手术。我们在一家一级学术创伤中心进行了一项回顾性队列研究,回顾了2018年至2020年间接受髋部骨折手术的425名老年患者(年龄>60岁)的记录,包括住院前接受直接口服抗凝剂治疗的一个亚组。该研究评估了需要早期再次手术的并发症发生率。在425名患者中,只有9名(2%)在出院后一个月内需要再次手术,其中2名(0.5%)接受长期抗凝治疗。所有再次手术均不紧急,且均在再次入院至少24小时后进行。研究结果显示,接受髋部骨折手术的患者再次手术发生率非常低,再次入院后24小时内未进行再次手术。因此,我们认为髋部骨折手术后出院时恢复长期直接口服抗凝剂是一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1346/10780080/09fd9c7581b0/jcm-13-00017-g001.jpg

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