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基于临床数据的人工神经网络对颈脊髓损伤预后预测准确性的验证

Verification of the Accuracy of Cervical Spinal Cord Injury Prognosis Prediction Using Clinical Data-Based Artificial Neural Networks.

作者信息

Kishikawa Jun, Kobayakawa Kazu, Saiwai Hirokazu, Yokota Kazuya, Kubota Kensuke, Hayashi Tetsuo, Morishita Yuichiro, Masuda Muneaki, Sakai Hiroaki, Kawano Osamu, Nakashima Yasuharu, Maeda Takeshi

机构信息

Department of Orthopedic Surgery, Spinal Injuries Center, Fukuoka 820-8508, Japan.

Department of Orthopedic Surgery, Kyushu University, Fukuoka 812-8582, Japan.

出版信息

J Clin Med. 2024 Jan 1;13(1):253. doi: 10.3390/jcm13010253.

Abstract

BACKGROUND

In patients with cervical spinal cord injury (SCI), we need to make accurate prognostic predictions in the acute phase for more effective rehabilitation. We hypothesized that a multivariate prognosis would be useful for patients with cervical SCI.

METHODS

We made two predictive models using Multiple Linear Regression (MLR) and Artificial Neural Networks (ANNs). We adopted MLR as a conventional predictive model. Both models were created using the same 20 clinical parameters of the acute phase data at the time of admission. The prediction results were classified by the ASIA Impairment Scale. The training data consisted of 60 cases, and prognosis prediction was performed for 20 future cases (test cohort). All patients were treated in the Spinal Injuries Center (SIC) in Fukuoka, Japan.

RESULTS

A total of 16 out of 20 cases were predictable. The correct answer rate of MLR was 31.3%, while the rate of ANNs was 75.0% (number of correct answers: 12).

CONCLUSION

We were able to predict the prognosis of patients with cervical SCI from acute clinical data using ANNs. Performing effective rehabilitation based on this prediction will improve the patient's quality of life after discharge. Although there is room for improvement, ANNs are useful as a prognostic tool for patients with cervical SCI.

摘要

背景

对于颈脊髓损伤(SCI)患者,我们需要在急性期做出准确的预后预测,以便进行更有效的康复治疗。我们假设多变量预后模型对颈SCI患者有用。

方法

我们使用多元线性回归(MLR)和人工神经网络(ANNs)建立了两个预测模型。我们采用MLR作为传统的预测模型。两个模型均使用入院时急性期数据的相同20个临床参数创建。预测结果根据美国脊髓损伤协会(ASIA)损伤分级进行分类。训练数据包括60例病例,并对20例未来病例(测试队列)进行预后预测。所有患者均在日本福冈的脊髓损伤中心(SIC)接受治疗。

结果

20例病例中有16例可预测。MLR的正确回答率为31.3%,而ANNs的正确回答率为75.0%(正确回答数:12)。

结论

我们能够使用ANNs从急性临床数据预测颈SCI患者的预后。基于此预测进行有效的康复治疗将改善患者出院后的生活质量。尽管仍有改进空间,但ANNs作为颈SCI患者的预后工具是有用的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98af/10779821/046eb508c9a6/jcm-13-00253-g001.jpg

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