Oesterling J E, Epstein J I, Gearhart J P
J Urol. 1987 Mar;137(3):398-400. doi: 10.1016/s0022-5347(17)44047-x.
Primary epithelial tumors of the bladder are extremely rare in children and adolescents. We report a case of transitional cell carcinoma in an adolescent with Turner's syndrome. The patient presented with intermittent gross hematuria and mild dysuria. A mass was identified on the trigone of the bladder near the left ureteral orifice, and histological evaluation revealed grade II to III in situ papillary transitional cell carcinoma with foci of submucosal invasion. Transurethral resection of the tumor was performed, and the patient remains free of disease 2 1/2 years later. The literature on transitional cell carcinoma of the bladder in children is reviewed.
原发性膀胱上皮肿瘤在儿童和青少年中极为罕见。我们报告一例患有特纳综合征的青少年发生移行细胞癌的病例。该患者表现为间歇性肉眼血尿和轻度排尿困难。在膀胱三角区靠近左输尿管口处发现一个肿块,组织学评估显示为II至III级原位乳头状移行细胞癌,并伴有黏膜下浸润灶。对肿瘤进行了经尿道切除术,2年半后患者仍无疾病复发。本文对儿童膀胱移行细胞癌的文献进行了综述。