School of Public Health, University of Alberta, Edmonton, Alberta.
Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, Canada.
Hosp Pediatr. 2024 Feb 1;14(2):93-101. doi: 10.1542/hpeds.2023-007457.
To estimate associations between clinical and socioeconomic variables and hospital days and emergency department (ED) visits for children with medical complexity (CMCs) for 5 years after index admission.
Retrospective, longitudinal, population-based cohort study of CMCs in Alberta (n = 12 621) diagnosed between 2010 and 2013 using administrative data linked to socioeconomic data. The primary outcomes were annual cumulative numbers of hospital days and ED visits for 5 years after index admission. Data were analyzed using mixed-effect hurdle regression.
Among CMCs utilizing resources, those with more chronic medications had more hospital days (relative difference [RD] 3.331 for ≥5 vs 0 medications in year 1, SE 0.347, P value < .001) and ED visits (RD 1.836 for 0 vs ≥5 medications in year 1, SE 0.133, P value < .001). Among these CMCs, initial length of stay had significant, positive associations with hospital days (RD 1.960-5.097, SE 0.161-0.610, P value < .001 outside of the gastrointestinal and hematology and immunodeficiency groups). Those residing in rural or remote areas had more ED visits than those in urban or metropolitan locations (RD 1.727 for rural versus urban, SE 0.075, P < .001). Material and social deprivation had significant, positive associations with number of ED visits.
Clinical factors are more strongly associated with hospitalizations and socioeconomic factors with ED visits. Policy administrators and researchers aiming to optimize resource use and improve outcomes for CMCs should consider interventions that include both clinical care and socioeconomic support.
估计临床和社会经济变量与儿童医疗复杂性(CMC)患者索引入院后 5 年内住院天数和急诊就诊次数之间的关联。
使用行政数据与社会经济数据链接,对 2010 年至 2013 年期间在艾伯塔省诊断为 CMC 的患者进行回顾性、纵向、基于人群的队列研究。主要结局为索引入院后 5 年内每年累计住院天数和急诊就诊次数。使用混合效应障碍回归分析数据。
在利用资源的 CMC 中,使用慢性药物较多的患者住院天数更多(第 1 年中,≥5 种药物与 0 种药物相比的相对差异[RD]为 3.331,SE 为 0.347,P 值<0.001),急诊就诊次数也更多(第 1 年中,0 种药物与≥5 种药物相比的 RD 为 1.836,SE 为 0.133,P 值<0.001)。在这些 CMC 中,初始住院时间与住院天数呈显著正相关(RD 为 1.960-5.097,SE 为 0.161-0.610,P 值<0.001,除外胃肠道和血液学和免疫缺陷组)。居住在农村或偏远地区的患者比居住在城市或大都市区的患者急诊就诊次数更多(农村与城市相比的 RD 为 1.727,SE 为 0.075,P<0.001)。物质和社会剥夺与急诊就诊次数呈显著正相关。
临床因素与住院治疗的相关性更强,而社会经济因素与急诊就诊的相关性更强。旨在优化 CMC 资源利用和改善结局的政策制定者和研究人员应考虑包括临床护理和社会经济支持在内的干预措施。