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从诊断到治疗:探索宫颈上皮内瘤变的最新管理趋势

From Diagnosis to Treatment: Exploring the Latest Management Trends in Cervical Intraepithelial Neoplasia.

作者信息

Gupta Saloni, Nagtode Nikhilesh, Chandra Vaibhav, Gomase Kavita

机构信息

Community Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Obstetrics and Gynecology, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2023 Dec 10;15(12):e50291. doi: 10.7759/cureus.50291. eCollection 2023 Dec.

Abstract

Cervical intraepithelial neoplasia (CIN) stands as a precancerous condition with the potential to progress to invasive cervical cancer. This comprehensive review explores the intricacies of CIN management, beginning with its definition, classification, and etiology. It emphasizes the significance of early detection and outlines the latest trends in diagnosis, including Pap smears, human papillomavirus (HPV) testing, and colposcopy. Grading and staging, pivotal in treatment selection, are elucidated. Current management approaches, encompassing watchful waiting, surgical interventions, emerging minimally invasive techniques, and immunotherapy, are detailed. The factors influencing treatment decisions, informed consent, and patient education are discussed. Potential complications following treatment, the importance of long-term follow-up, and the role of HPV vaccination in prevention are underscored. Finally, the review looks to the future, discussing advances in detection, novel treatments, and the promise of precision medicine. In conclusion, early detection and management remain the cornerstone of CIN care, offering hope for a future where cervical cancer is a preventable and treatable condition.

摘要

宫颈上皮内瘤变(CIN)是一种癌前病变,有可能发展为浸润性宫颈癌。这篇综述探讨了CIN管理的复杂性,从其定义、分类和病因开始。它强调了早期检测的重要性,并概述了诊断的最新趋势,包括巴氏涂片、人乳头瘤病毒(HPV)检测和阴道镜检查。阐述了在治疗选择中起关键作用的分级和分期。详细介绍了当前的管理方法,包括观察等待、手术干预、新兴的微创技术和免疫疗法。讨论了影响治疗决策、知情同意和患者教育的因素。强调了治疗后潜在的并发症、长期随访的重要性以及HPV疫苗接种在预防中的作用。最后,综述展望未来,讨论了检测方面的进展、新的治疗方法以及精准医学的前景。总之,早期检测和管理仍然是CIN护理的基石,为宫颈癌成为可预防和可治疗疾病的未来带来了希望。

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