Department of Endocrinology, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
J Int Med Res. 2024 Jan;52(1):3000605231223040. doi: 10.1177/03000605231223040.
Atrioventricular block (AVB) is a rare cardiac manifestation of hyperthyroidism (HTH). The scientific literature contains multiple reports of AVB in patients with HTH, ranging from subclinical to overt HTH and even thyroid storm. However, much remains unknown about the true prevalence, clinical course, optimal management, and outcomes of AVB in patients with HTH. Such patients are possibly overtreated with pacemakers because of a lack of understanding that AVB might be secondary to the hyperthyroid state and thus reversible. This narrative review discusses the pathophysiology of AVB in patients with HTH in the context of the available evidence.
房室传导阻滞(AVB)是甲状腺功能亢进症(HTH)的一种罕见心脏表现。科学文献中有多项关于 HTH 患者 AVB 的报告,范围从亚临床到显性 HTH 甚至甲状腺危象。然而,对于 HTH 患者的 AVB 的真实患病率、临床过程、最佳管理和结局,仍有许多未知之处。由于缺乏对 AVB 可能是由甲状腺功能亢进状态引起的、因此是可逆的这一认识,这些患者可能会因起搏器过度治疗。本叙述性综述根据现有证据讨论了 HTH 患者 AVB 的病理生理学。