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一名接受甲状腺功能正常的格雷夫斯病治疗的患者出现未解决的完全性心脏传导阻滞:诊断难题

Unresolved Complete Heart Block in a Patient Treated for Euthyroid Graves' Disease: A Diagnostic Dilemma.

作者信息

Natesan Tharun Adithya, Murshed Mehereen, Abraham Sandhya, Fernandez Cornelius

机构信息

Internal Medicine, Nottingham University Hospital NHS Trust, Nottingham, GBR.

Internal Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, GBR.

出版信息

Cureus. 2024 Dec 15;16(12):e75746. doi: 10.7759/cureus.75746. eCollection 2024 Dec.

Abstract

The cardiovascular implications of thyroid disease have been recognized as one of the most characteristic signs that result from the effect of thyroid hormone (TH). Both hyperthyroidism and hypothyroidism produce changes in cardiac contractility, myocardial oxygen consumption, cardiac output, blood pressure, and systemic vascular resistance. The bradyarrhythmias, including atrioventricular block and sick sinus syndrome, are exceedingly rare in hyperthyroidism.Studies have stated that atrioventricular block complicating a hyperthyroid state is the rarest and most under-studied cardiac complication. Only a few case reports have described this association, which is commonly seen with acute inflammatory states, infections, or medications. Here, we present the case of a 16-year-old girl who presented with thyrotoxicosis and was incidentally found to have asymptomatic complete heart block (CHB) in the setting of newly diagnosed Graves' disease. This case report explores the course of her treatment and possible causes given the rarity of presentation.

摘要

甲状腺疾病对心血管系统的影响已被认为是甲状腺激素(TH)作用产生的最典型体征之一。甲状腺功能亢进和甲状腺功能减退都会引起心脏收缩力、心肌耗氧量、心输出量、血压和全身血管阻力的变化。包括房室传导阻滞和病态窦房结综合征在内的缓慢性心律失常在甲状腺功能亢进症中极为罕见。研究表明,并发甲状腺功能亢进状态的房室传导阻滞是最罕见且研究最少的心脏并发症。仅有少数病例报告描述了这种关联,常见于急性炎症状态、感染或药物治疗时。在此,我们报告一例16岁女孩,她因甲状腺毒症就诊,在新诊断的格雷夫斯病背景下偶然发现无症状性完全性心脏传导阻滞(CHB)。鉴于这种病例的罕见性,本病例报告探讨了她的治疗过程及可能的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2cf/11731699/2e9b431053e8/cureus-0016-00000075746-i01.jpg

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