Fu X, Tamozhnikov S S, Saprygin A E, Istomina N A, Klemeshova D I, Savostyanov A N
Novosibirsk State University, Novosibirsk, Russia.
Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia.
Vavilovskii Zhurnal Genet Selektsii. 2023 Dec;27(7):851-858. doi: 10.18699/VJGB-23-98.
The development of objective methods for assessing stress levels is an important task of applied neuroscience. Analysis of EEG recorded as part of a behavioral self-control program can serve as the basis for the development of test methods that allow classifying people by stress level. It is well known that participation in meditation practices leads to the development of skills of voluntary self-control over the individual's mental state due to an increased concentration of attention to themselves. As a consequence of meditation practices, participants can reduce overall anxiety and stress levels. The aim of our study was to develop, train and test a convolutional neural network capable of classifying individuals into groups of practitioners and non-practitioners of meditation by analysis of eventrelated brain potentials recorded during stop-signal paradigm. Four non-deep convolutional network architectures were developed, trained and tested on samples of 100 people (51 meditators and 49 non-meditators). Subsequently, all structures were additionally tested on an independent sample of 25 people. It was found that a structure using a one-dimensional convolutional layer combining the layer and a two-layer fully connected network showed the best performance in simulation tests. However, this model was often subject to overfitting due to the limitation of the display size of the data set. The phenomenon of overfitting was mitigated by changing the structure and scale of the model, initialization network parameters, regularization, random deactivation (dropout) and hyperparameters of cross-validation screening. The resulting model showed 82 % accuracy in classifying people into subgroups. The use of such models can be expected to be effective in assessing stress levels and inclination to anxiety and depression disorders in other groups of subjects.
开发评估压力水平的客观方法是应用神经科学的一项重要任务。作为行为自我控制程序一部分记录的脑电图分析可作为开发测试方法的基础,该方法能够根据压力水平对人进行分类。众所周知,参与冥想练习会由于对自身注意力的增强而导致对个人心理状态进行自愿自我控制技能的发展。作为冥想练习的结果,参与者可以降低总体焦虑和压力水平。我们研究的目的是通过分析在停止信号范式期间记录的事件相关脑电位,开发、训练和测试一个能够将个体分为冥想练习者和非冥想练习者组的卷积神经网络。开发了四种非深度卷积网络架构,并在100人(51名冥想者和49名非冥想者)的样本上进行了训练和测试。随后,所有结构在25人的独立样本上进行了额外测试。结果发现,一种使用结合了一维卷积层和两层全连接网络的结构在模拟测试中表现最佳。然而,由于数据集显示大小的限制,该模型经常出现过拟合现象。通过改变模型的结构和规模、初始化网络参数、正则化、随机失活(随机丢弃)和交叉验证筛选的超参数,减轻了过拟合现象。所得模型在将人分类为亚组方面显示出82%的准确率。预计使用此类模型在评估其他受试者群体的压力水平以及焦虑和抑郁障碍倾向方面将是有效的。