Breast Surgery, The Mount Sinai Hospital, New York, New York, USA
Breast Surgery, The Mount Sinai Hospital, New York, New York, USA.
BMJ Case Rep. 2024 Jan 12;17(1):e258609. doi: 10.1136/bcr-2023-258609.
Breast necrotising soft tissue infections (NSTIs) are rare surgical emergencies with limited cases described in the literature. Here, we discuss a unique case of a woman in her 70s who presented with newly diagnosed diabetes and a neglected right breast cancer associated with breast erythema, skin necrosis, crepitus on examination and breast soft tissue gas seen on CT requiring emergent total mastectomy with partial pectoralis muscle excision. Pathology revealed a 15 cm invasive mucinous adenocarcinoma and necrotising polymicrobial cellulitis with a large abscess cavity. She recovered from her surgery with strict glycaemic control and a 10-day course of antibiotics. Multidisciplinary tumour board recommended adjuvant anastrozole, abemaciclib and postmastectomy radiation to complete her oncological treatment. Although exceedingly rare, it is important that clinicians be aware of, promptly recognise and properly treat NSTIs of the breast, as correct care can be life-saving from both infection and malignancy.
乳房坏死性软组织感染(NSTIs)是罕见的外科急症,文献中描述的病例有限。在这里,我们讨论了一位 70 多岁女性的独特病例,她患有新诊断的糖尿病和被忽视的右乳腺癌,伴有乳房红斑、皮肤坏死、检查时出现捻发音,CT 显示乳房软组织积气,需要紧急行全乳房切除术和部分胸大肌切除术。病理显示 15 厘米浸润性黏液性腺癌和坏死性多微生物蜂窝织炎,伴有大脓肿腔。她通过严格的血糖控制和 10 天的抗生素疗程从手术中康复。多学科肿瘤委员会建议辅助使用阿那曲唑、阿贝西利和乳房切除术放疗来完成她的肿瘤治疗。虽然极其罕见,但临床医生了解、迅速识别和正确治疗乳房 NSTIs 非常重要,因为正确的治疗可以挽救生命,防止感染和恶性肿瘤。