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乳房坏疽性蜂窝织炎伴黏液性腺癌外生性。

Necrotising cellulitis of the breast associated with a fungating mucinous adenocarcinoma.

机构信息

Breast Surgery, The Mount Sinai Hospital, New York, New York, USA

Breast Surgery, The Mount Sinai Hospital, New York, New York, USA.

出版信息

BMJ Case Rep. 2024 Jan 12;17(1):e258609. doi: 10.1136/bcr-2023-258609.

Abstract

Breast necrotising soft tissue infections (NSTIs) are rare surgical emergencies with limited cases described in the literature. Here, we discuss a unique case of a woman in her 70s who presented with newly diagnosed diabetes and a neglected right breast cancer associated with breast erythema, skin necrosis, crepitus on examination and breast soft tissue gas seen on CT requiring emergent total mastectomy with partial pectoralis muscle excision. Pathology revealed a 15 cm invasive mucinous adenocarcinoma and necrotising polymicrobial cellulitis with a large abscess cavity. She recovered from her surgery with strict glycaemic control and a 10-day course of antibiotics. Multidisciplinary tumour board recommended adjuvant anastrozole, abemaciclib and postmastectomy radiation to complete her oncological treatment. Although exceedingly rare, it is important that clinicians be aware of, promptly recognise and properly treat NSTIs of the breast, as correct care can be life-saving from both infection and malignancy.

摘要

乳房坏死性软组织感染(NSTIs)是罕见的外科急症,文献中描述的病例有限。在这里,我们讨论了一位 70 多岁女性的独特病例,她患有新诊断的糖尿病和被忽视的右乳腺癌,伴有乳房红斑、皮肤坏死、检查时出现捻发音,CT 显示乳房软组织积气,需要紧急行全乳房切除术和部分胸大肌切除术。病理显示 15 厘米浸润性黏液性腺癌和坏死性多微生物蜂窝织炎,伴有大脓肿腔。她通过严格的血糖控制和 10 天的抗生素疗程从手术中康复。多学科肿瘤委员会建议辅助使用阿那曲唑、阿贝西利和乳房切除术放疗来完成她的肿瘤治疗。虽然极其罕见,但临床医生了解、迅速识别和正确治疗乳房 NSTIs 非常重要,因为正确的治疗可以挽救生命,防止感染和恶性肿瘤。

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引用本文的文献

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本文引用的文献

1
Necrotizing Soft Tissue Infections of the Breast: A Potentially Lethal Surgical Emergency.
Case Rep Surg. 2023 Jul 20;2023:4695019. doi: 10.1155/2023/4695019. eCollection 2023.
2
Breast rescue after necrotizing fasciitis.
Heliyon. 2022 Dec 10;8(12):e12305. doi: 10.1016/j.heliyon.2022.e12305. eCollection 2022 Dec.
3
Necrotizing Fasciitis of the Breast Requiring a Life-Saving Mastectomy: A Case Report and Literature Review.
Cureus. 2021 Nov 25;13(11):e19886. doi: 10.7759/cureus.19886. eCollection 2021 Nov.
4
Necrotizing Fasciitis of the Breast: A Case Report and Literature Review.
J Med Cases. 2019 Sep;10(9):288-292. doi: 10.14740/jmc3361. Epub 2019 Sep 26.
5
Management of Primary Necrotizing Fasciitis of the Breast: A Systematic Review.
Plast Surg (Oakv). 2020 Nov;28(4):215-221. doi: 10.1177/2292550320928557. Epub 2020 Jun 4.
6
Necrotizing Fasciitis of the Breast: Case Report with Literature Review.
Case Rep Surg. 2018 Oct 23;2018:1370680. doi: 10.1155/2018/1370680. eCollection 2018.
7
Necrotizing soft tissue infections: review and current concepts in treatment, systems of care, and outcomes.
Curr Probl Surg. 2014 Aug;51(8):344-62. doi: 10.1067/j.cpsurg.2014.06.001. Epub 2014 Jun 12.
8
Sonographic and pathologic image analysis of pure mucinous carcinoma of the breast.
Ultrasound Med Biol. 2013 Jul;39(7):1158-67. doi: 10.1016/j.ultrasmedbio.2013.02.014. Epub 2013 May 15.
9
Outcome of pure mucocele-like lesions diagnosed on breast core biopsy.
Histopathology. 2013 May;62(6):894-8. doi: 10.1111/his.12081. Epub 2013 Feb 12.
10
Shared management of a rare necrotizing soft tissue infection of the breast.
Breast J. 2009 May-Jun;15(3):321-3. doi: 10.1111/j.1524-4741.2009.00731.x.

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