Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Department of Obstetrics and Gynecology, Chia-Yi Chang Gung Memorial Hospital, Chia-Yi, Taiwan.
Taiwan J Obstet Gynecol. 2024 Jan;63(1):29-36. doi: 10.1016/j.tjog.2023.09.018.
Probiotics, live microorganisms that confer health benefits to the host when administered in adequate amounts, have gained considerable attention for their potential role in maintaining women's health. This overview summarizes key clinical findings on the beneficial effects of probiotics in various aspects of women's health. Probiotics, particularly Lactobacillus species, contribute to vaginal health by promoting a balanced vaginal microbiome to prevent infections and maintain an acidic environment. In gynecologic conditions, probiotics show potential in preventing and managing bacterial vaginosis, vulvovaginal candidiasis, and sexually transmitted infections. Probiotic supplementation has also been associated with improvements in metabolic parameters and menstrual irregularities in polycystic ovary syndrome patients. During pregnancy, probiotics may be helpful in reducing the risk of gestational diabetes, maternal group B streptococcal colonization, obstetric anemia, and postpartum mastitis. In recent years, the potential role of probiotics in the prevention and management of gynecologic cancer has gained attention. Further research is needed to better understand the specific mechanisms and determine the optimal Lactobacillus strains and dosages regimens for gynecologic cancer prevention and therapy. In conclusion, probiotics offer a non-invasive and cost-effective approach to support women's health and prevent obstetric and gynecologic complications.
益生菌是一种有益宿主健康的活菌，当以足够的剂量给予时，它们在维持女性健康方面的潜在作用引起了相当大的关注。本篇综述总结了益生菌在女性健康各个方面的有益作用的关键临床发现。益生菌，特别是乳杆菌属，通过促进阴道微生物群落的平衡来预防感染并维持酸性环境，从而有助于阴道健康。在妇科疾病方面，益生菌在预防和治疗细菌性阴道病、外阴阴道念珠菌病和性传播感染方面显示出潜力。益生菌补充剂还与多囊卵巢综合征患者代谢参数和月经不规律的改善有关。在怀孕期间，益生菌可能有助于降低妊娠期糖尿病、B 组链球菌定植、产科贫血和产后乳腺炎的风险。近年来，益生菌在预防和治疗妇科癌症方面的潜在作用引起了关注。需要进一步的研究来更好地了解具体的机制，并确定预防和治疗妇科癌症的最佳乳杆菌菌株和剂量方案。总之，益生菌为支持女性健康和预防产科和妇科并发症提供了一种非侵入性和具有成本效益的方法。
