Physiotherapy Program, Department of Therapy and Rehabilitation, Vocational School of Health Sciences, Selcuk University, Konya, Turkey.
Gulhane Faculty of Physiotherapy and Rehabilitation, University of Health Sciences, Ankara, Turkey.
J Back Musculoskelet Rehabil. 2024;37(3):793-799. doi: 10.3233/BMR-230293.
Osteoarthritis (OA) is a pathology that frequently affects the geriatric population.
To investigate the extent to which pain, functionality, and quality of life change over the progression of OA grades.
The study included 161 patients with bilateral OA, whose disease stages ranged from 1 to 4 according to the Kellgren-Lawrence radiographic classification system. Pain was assessed using the Visual Analog Scale (VAS), functionality using the two-minute walk test and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire, and quality of life using the Nottingham Health Profile (NHP).
There were significant differences between the groups in terms of age, weight, and body mass index. The VAS, two-minute walk test, and WOMAC scores also significantly differed between the groups (p< 0.05). There was a significant difference between the groups in all domains of the NHP, except for energy (p< 0.05). The two-minute walk test score was negatively correlated with all the remaining evaluation parameters (p< 0.05). No correlation was found between the energy domain of the NHP and body mass index, the VAS score, the two-minute walk test distance, or the total WOMAC score (p> 0.05).
After grade 1, the functional impacts of OA on patients increased by an average of four times. Pain was one of the most basic symptoms, the severity of which started to increase in grade 2. With the added effect of diminishing walking capacity over time, the reduction in the quality of life of the patients accelerated as the OA grade progressed.
骨关节炎(OA)是一种常见于老年人群的疾病。
研究 OA 分级进展过程中疼痛、功能和生活质量的变化程度。
本研究纳入了 161 例双侧 OA 患者,其疾病分期根据 Kellgren-Lawrence 放射学分类系统为 1 至 4 级。使用视觉模拟评分(VAS)评估疼痛,使用两分钟步行试验和西部安大略省和麦克马斯特大学骨关节炎指数(WOMAC)问卷评估功能,使用诺丁汉健康调查问卷(NHP)评估生活质量。
在年龄、体重和体重指数方面,各组间存在显著差异。VAS、两分钟步行试验和 WOMAC 评分也在组间存在显著差异(p<0.05)。NHP 的所有领域除能量外(p<0.05),组间差异均有统计学意义。两分钟步行试验评分与所有其余评估参数呈负相关(p<0.05)。NHP 的能量域与体重指数、VAS 评分、两分钟步行试验距离或 WOMAC 总分之间无相关性(p>0.05)。
在分级 1 之后,OA 对患者的功能影响平均增加了四倍。疼痛是最基本的症状之一,其严重程度在分级 2 时开始增加。随着步行能力随时间逐渐下降的附加效应,随着 OA 分级的进展,患者生活质量的下降速度加快。