Department of Medicine, University of Otago Wellington, PO Box 7343, Wellington 6242, New Zealand.
Research Centre for Hauora and Health, Massey University, Wellington, New Zealand.
J Neurol Sci. 2024 Feb 15;457:122870. doi: 10.1016/j.jns.2024.122870. Epub 2024 Jan 8.
Global industrialisation and urbanisation has led to an increased interest in the link between the environment and health. Stroke is a major cause of morbidity and mortality, and there is increased evidence that environmental factors may affect both the incidence and severity of stroke. This review summarises the evidence for relationship between green space exposure and stroke incidence and outcomes.
We conducted a literature search in Medline and Scopus until 1 August 2023, and screened references of relevant articles. Selected articles were appraised for their relevance, and critically reviewed. The findings were thematically categorised.
Of the 1342 papers identified, 27 were included. These involved a mix of study designs (cohort, cross-sectional, quasi-experimental, time stratified case crossover and ecological). There was consistent evidence indicating a protective association between green space exposure and disability and stroke-related death with mortality hazard ratios between 0.66 and 0.95. Most studies also showed that green space was inversely associated with stroke risk, with risk estimates from studies showing a protective effect ranging between 0.4 and 0.98; however, results were more mixed and some did not reach statistical significance. The moderating effects of green spaces on ambient temperatures, noise and air pollution, and psychosocial health plus greater enjoyment and opportunity for exercise and enrichment of the human microbiome may underly these associations.
There is likely some protective effect of green space on stroke, with the benefits most convincingly shown for post-stroke outcomes. More research is recommended to confirm the protective association between green space exposure and reduced stroke risk.
全球工业化和城市化导致人们对环境与健康之间的关系产生了浓厚的兴趣。中风是发病率和死亡率的主要原因,越来越多的证据表明,环境因素可能会影响中风的发病率和严重程度。本综述总结了暴露于绿色空间与中风发病率和结局之间关系的证据。
我们在 Medline 和 Scopus 中进行了文献检索,检索时间截至 2023 年 8 月 1 日,并筛选了相关文章的参考文献。选择的文章经过相关性评估和批判性审查。研究结果按照主题进行分类。
在确定的 1342 篇论文中,有 27 篇被纳入。这些研究涉及多种研究设计(队列研究、横断面研究、准实验研究、时间分层病例交叉研究和生态学研究)。有一致的证据表明,暴露于绿色空间与残疾和中风相关死亡之间存在保护关联,死亡率的危害比在 0.66 至 0.95 之间。大多数研究还表明,绿色空间与中风风险呈负相关,研究中的风险估计值表明保护作用的范围在 0.4 至 0.98 之间;然而,结果更为混杂,有些结果没有达到统计学意义。绿色空间对环境温度、噪声和空气污染的调节作用,以及对心理社会健康的影响,加上更多的锻炼机会和丰富人类微生物组,可能是这些关联的基础。
绿色空间可能对中风有一定的保护作用,对中风后结局的益处最为明显。需要进一步的研究来证实暴露于绿色空间与降低中风风险之间的保护关联。