胃肠道肿瘤放疗的多学科诊断与治疗营养支持干预：对营养及生活质量的影响
Multidisciplinary diagnosis and treatment nutritional support intervention for gastrointestinal tumor radiotherapy: Impact on nutrition and quality of life.
作者信息
Hui Lin, Zhang Ying-Ying, Hu Xiao-Dan
机构信息
Head, Neck and Chest Radiotherapy Department 1, Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China.
Department of Gastroenterology, The People's Hospital of Danyang, Danyang 212300, Jiangsu Province, China.
出版信息
World J Gastrointest Surg. 2023 Dec 27;15(12):2719-2726. doi: 10.4240/wjgs.v15.i12.2719.
BACKGROUND
Gastrointestinal tumors are a major cause of cancer-related deaths and have become a major public health problem. This study aims to provide a scientific basis for improving clinical treatment effects, quality of life, and prognosis of patients with gastrointestinal tumors.
AIM
To explore the clinical effect of the multidisciplinary diagnosis and treatment (MDT) nutrition intervention model on patients with gastrointestinal tumors.
METHODS
This was a case control study which included patients with gastrointestinal tumors who received radiotherapy at the Department of Oncology between January 2021 and January 2023. Using a random number table, 120 patients were randomly divided into MDT and control groups with 60 patients in each group. To analyze the effect of MDT on the nutritional status and quality of life of the patients, the nutritional status and quality of life scores of the patients were measured before and after the treatment.
RESULTS
Albumin (ALB), transferrin (TRF), hemoglobin (Hb), and total protein (TP) levels significantly decreased after the treatment. The control group had significantly lower ALB, TRF, Hb, and TP levels than the MDT group, and the differences in these levels between the two groups were statistically significant ( < 0.05). After the treatment, the MDT group had significantly more well-nourished patients than the control group ( < 0.05). The quality of life total score, somatic functioning, role functioning, and emotional functioning were higher in the MDT group than in the control group. By contrast, pain, fatigue, nausea, and vomiting scores were lower in the MDT group than in the control group ( < 0.05).
CONCLUSION
MDT nutritional intervention model effectively improves the nutritional status and quality of life of the patients. The study provides a rigorous theoretical basis for improving the prognosis of cancer patients. In the future, we intend to provide additional treatment methods for improving the quality of life of patients with cancer.
背景
胃肠道肿瘤是癌症相关死亡的主要原因，已成为一个重大的公共卫生问题。本研究旨在为提高胃肠道肿瘤患者的临床治疗效果、生活质量和预后提供科学依据。
目的
探讨多学科诊断与治疗（MDT）营养干预模式对胃肠道肿瘤患者的临床效果。
方法
这是一项病例对照研究，纳入了2021年1月至2023年1月在肿瘤科接受放疗的胃肠道肿瘤患者。使用随机数字表，将120例患者随机分为MDT组和对照组，每组60例。为分析MDT对患者营养状况和生活质量的影响，在治疗前后测量患者的营养状况和生活质量评分。
结果
治疗后白蛋白（ALB）、转铁蛋白（TRF）、血红蛋白（Hb）和总蛋白（TP）水平显著下降。对照组的ALB、TRF、Hb和TP水平显著低于MDT组，两组之间这些水平的差异具有统计学意义（<0.05）。治疗后，MDT组营养良好的患者明显多于对照组（<0.05）。MDT组的生活质量总分、躯体功能、角色功能和情感功能均高于对照组。相比之下，MDT组的疼痛、疲劳、恶心和呕吐评分低于对照组（<0.05）。
结论
MDT营养干预模式有效改善了患者的营养状况和生活质量。该研究为改善癌症患者的预后提供了严谨的理论依据。未来，我们打算提供更多改善癌症患者生活质量的治疗方法。
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