Schnoz M, Ryser D H, Barandun S, Eckmann L
Helv Chir Acta. 1979 May;46(1-2):111-3.
In a clinical study the tolerance and efficacy of a gamma-globulin, treated at pH 4, has been studied. This preparation manufactured by the "Zentrallaboratorium des Blutspendedienstes SRK" can be given intravenously without any risk of untoward reactions. It has been applied in high dosages up to 99 g per week. In 15 cases with primary humoral immunodeficiency, the frequency and the severity of acute bacterial infections were markedly reduced or completely absent. In 16 patients without antibody deficiency but suffering from severe septic-toxic infections, results with Immunglobulin SRK were encouraging and warrant further controlled studies.
在一项临床研究中，对在pH 4条件下处理的一种γ-球蛋白的耐受性和疗效进行了研究。这种由“SRK血液捐献服务中央实验室”生产的制剂可以静脉注射，不会有任何不良反应的风险。它已被以高达每周99克的高剂量使用。在15例原发性体液免疫缺陷患者中，急性细菌感染的频率和严重程度明显降低或完全没有出现。在16例无抗体缺乏但患有严重脓毒症中毒感染的患者中，SRK免疫球蛋白的治疗结果令人鼓舞，值得进一步进行对照研究。
