静脉注射免疫球蛋白治疗抗体缺乏症。
Intravenous immunoglobulin therapy for antibody deficiency.
作者信息
Nolte M T, Pirofsky B, Gerritz G A, Golding B
出版信息
Clin Exp Immunol. 1979 May;36(2):237-43.
Abstract
Twenty patients with antibody deficiency were treated at random with either intramuscular immune serum globulin (ISG) or intravenous modified immune serum globulin (M-ISG). Fourteen patients received of 259 M-ISG infusions during 242 months of treatment. Catastrophic vasomotor reactions were not observed. A single dose of 150 mg/kilo M-ISG increased serum IgG values a mean 248 mg%. Intravenous M-ISG therapy was effective in reducing the incidence of acute infections. Subjects receiving M-ISG developed 0.103 acute infections per month of treatment. Patients injected with ISG had 0.295 acute infections per month of treatment. Seven subjects had separate courses of both intravenous M-ISG and intramuscular ISG. Acute infections per month of treatment for M-ISG and ISG were 0.104 and 0.406, respectively.
摘要
20名抗体缺乏患者被随机分为两组，分别接受肌肉注射免疫血清球蛋白（ISG）或静脉注射改良免疫血清球蛋白（M-ISG）治疗。在242个月的治疗期间，14名患者接受了259次M-ISG输注。未观察到严重的血管舒缩反应。单剂量150mg/kg的M-ISG可使血清IgG值平均升高248mg%。静脉注射M-ISG疗法可有效降低急性感染的发生率。接受M-ISG治疗的受试者在每月治疗期间发生0.103次急性感染。注射ISG的患者每月治疗期间发生0.295次急性感染。7名受试者分别接受了静脉注射M-ISG和肌肉注射ISG的疗程。M-ISG和ISG每月治疗期间的急性感染发生率分别为0.104和0.406。
相似文献
1
Intravenous immunoglobulin therapy for antibody deficiency.静脉注射免疫球蛋白治疗抗体缺乏症。
Clin Exp Immunol. 1979 May;36(2):237-43.
2
[Intravenous immunoglobulin administration for antibody deficiency (author's transl)].
Dtsch Med Wochenschr. 1980 Jul 11;105(28):993-7. doi: 10.1055/s-2008-1070798.
3
4
Intravenous immune globulin therapy for antibody immunodeficiency.
Clin Ther. 1984;7(1):69-72.
5
[Treatment of primary immunodeficiencies with intravenous gamma globulin].[静脉注射丙种球蛋白治疗原发性免疫缺陷病]
An Esp Pediatr. 1987 Dec;27(6):411-5.
6
Replacement therapy with high dose intravenous gamma-globulin improves chronic sinopulmonary disease in patients with hypogammaglobulinemia.大剂量静脉注射γ-球蛋白替代疗法可改善低丙种球蛋白血症患者的慢性鼻窦肺部疾病。
Pediatr Infect Dis J. 1988 May;7(5 Suppl):S92-6.
7
[Deficiency in immunoglobulin subclasses as cause of increased infection susceptibility--a family study].[免疫球蛋白亚类缺乏作为感染易感性增加的原因——一项家族研究]
Schweiz Med Wochenschr. 1991 Feb 2;121(5):133-44.
8
IUIS/WHO notice. Appropriate uses of human immunoglobulin in clinical practice.国际免疫学会联盟/世界卫生组织公告。人免疫球蛋白在临床实践中的合理应用。
Clin Exp Immunol. 1983 May;52(2):417-22.
9
10
[Clinical results with a new intravenous immunoglobulin preparation (author's transl)].
Dtsch Med Wochenschr. 1980 Nov 28;105(48):1675-80. doi: 10.1055/s-2008-1070935.
引用本文的文献
1
Intravenous immunoglobulin and the current risk of moderate and severe anaphylactic events, a cohort study.静脉注射免疫球蛋白与当前中度和重度过敏反应事件的风险：一项队列研究。
Clin Exp Immunol. 2021 Dec;206(3):384-394. doi: 10.1111/cei.13665. Epub 2021 Oct 17.
2
Limited Innovations After More Than 65 Years of Immunoglobulin Replacement Therapy: Potential of IgA- and IgM-Enriched Formulations to Prevent Bacterial Respiratory Tract Infections.免疫球蛋白替代疗法超过 65 年后的有限创新：富含 IgA 和 IgM 的制剂预防细菌性呼吸道感染的潜力。
Front Immunol. 2018 Aug 23;9:1925. doi: 10.3389/fimmu.2018.01925. eCollection 2018.
3
Long-term Clinical Outcome of Antibody Replacement Therapy in Humoral Immunodeficient Adults With Respiratory Tract Infections.呼吸道感染的体液免疫缺陷成人的抗体替代疗法的长期临床结果。
EBioMedicine. 2017 Apr;18:254-260. doi: 10.1016/j.ebiom.2017.03.025. Epub 2017 Mar 21.
4
Clinical Experience with Octagam® 10 %, a solvent detergent virus inactivated intravenous immunoglobulin: a Canadian retrospective review of utilization.Octagam® 10%（一种经溶剂去污剂灭活病毒的静脉注射免疫球蛋白）的临床经验：加拿大使用情况的回顾性研究
Allergy Asthma Clin Immunol. 2016 Jul 27;12:32. doi: 10.1186/s13223-016-0138-9. eCollection 2016.
5
Hypermucoviscous Klebsiella syndrome without liver abscess in a patient with immunoglobulin g2 immune deficiency.免疫球蛋白 G2 缺陷患者的无肝脓肿高黏液化脓性克雷伯菌综合征。
Open Forum Infect Dis. 2014 Sep 9;1(2):ofu080. doi: 10.1093/ofid/ofu080. eCollection 2014 Sep.
6
Review of intravenous immunoglobulin replacement therapy trials for primary humoral immunodeficiency patients.原发性体液免疫缺陷患者静脉注射免疫球蛋白替代治疗试验的综述。
Infection. 2012 Dec;40(6):601-11. doi: 10.1007/s15010-012-0323-9. Epub 2012 Sep 12.
7
Subcutaneous immunoglobulin therapy: a new option for patients with primary immunodeficiency diseases.皮下免疫球蛋白疗法：原发性免疫缺陷病患者的一种新选择。
Biologics. 2012;6:277-87. doi: 10.2147/BTT.S25188. Epub 2012 Aug 24.
8
Progress in gammaglobulin therapy for immunodeficiency: from subcutaneous to intravenous infusions and back again.免疫缺陷症的丙种球蛋白治疗进展：从皮下注射到静脉输注，再到回归。
J Clin Immunol. 2012 Dec;32(6):1153-64. doi: 10.1007/s10875-012-9740-x. Epub 2012 Jul 25.
9
Common variable immunodeficiency complicated with hemolytic uremic syndrome.常见可变免疫缺陷并发溶血尿毒综合征。
Ups J Med Sci. 2012 Mar;117(1):67-71. doi: 10.3109/03009734.2011.635815. Epub 2011 Nov 7.
10
Efficacy and safety of subcutaneous vivaglobin® replacement therapy in previously untreated patients with primary immunodeficiency: a prospective, multicenter study.皮下注射 vivaglobin® 替代治疗对既往未治疗的原发性免疫缺陷患者的疗效和安全性：一项前瞻性、多中心研究。
J Clin Immunol. 2011 Dec;31(6):952-61. doi: 10.1007/s10875-011-9588-5. Epub 2011 Sep 20.
本文引用的文献
1
[On new possibilities of intravenous gamma globulin administration].[关于静脉注射γ-球蛋白给药的新可能性]
Dtsch Med Wochenschr. 1962 Aug 24;87:1643-4 passim. doi: 10.1055/s-0028-1113997.
2
Intravenous administration of human gamma-globulin.静脉注射人γ球蛋白。
Vox Sang. 1962;7:157-74. doi: 10.1111/j.1423-0410.1962.tb03240.x.
3
The agammaglobulinemias; relations and implications.
Am J Med. 1957 Dec;23(6):917-27. doi: 10.1016/0002-9343(57)90302-9.
4
Agammaglobulinemia, congenital, acquired and transient forms.无丙种球蛋白血症，包括先天性、获得性和暂时性形式。
Prog Hematol. 1956;1:318-29.
5
Immunochemical quantitation of antigens by single radial immunodiffusion.通过单向辐射免疫扩散法对抗原进行免疫化学定量。
Immunochemistry. 1965 Sep;2(3):235-54. doi: 10.1016/0019-2791(65)90004-2.
6
Survival studies on a commercial preparation of intravenous human gammaglobulin labelled with 131-I.
Australas Ann Med. 1969 Aug;18(3):271-6. doi: 10.1111/imj.1969.18.3.271.
7
Intravenous gamma globulin. Metabolism of gamma globulin fragments in normal and agammaglobulinemic persons.静脉注射丙种球蛋白。正常人和无丙种球蛋白血症患者体内丙种球蛋白片段的代谢。
N Engl J Med. 1968 Apr 25;278(17):919-23. doi: 10.1056/NEJM196804252781701.
8
Turnover of standard-gammaglobulin, pH-4-gammaglobulin and pepsin desaggregated gammaglobulin and clinical implications.
Vox Sang. 1967 Jul;13(1):93-102.
9
The preparation of plasmin treated immune serum globulin for intravenous use.静脉注射用纤溶酶处理的免疫血清球蛋白的制备。
Vox Sang. 1967 Jul;13(1):71-84.
10
Studies with intravenous gamma globulin.
Vox Sang. 1967 Jul;13(1):102-3.
Zotero 插件