Australian Institute of Health Innovation, Macquarie University, Level 6, 75 Talavera Road, Sydney, NSW, Australia.
NSW Biostatistics Training Program, NSW Ministry of Health, Sydney, NSW, Australia.
ESC Heart Fail. 2024 Apr;11(2):962-973. doi: 10.1002/ehf2.14644. Epub 2024 Jan 16.
Reducing preventable hospitalization for congestive heart failure (CHF) patients is a challenge for health systems worldwide. CHF patients who also have a recent or ongoing mental disorder may have worse health outcomes compared with CHF patients with no mental disorders. This study examined the impact of mental disorders on 28 day unplanned readmissions of CHF patients.
This retrospective cohort study used population-level linked public and private hospitalization and death data of adults aged ≥18 years who had a CHF admission in New South Wales, Australia, between 1 January 2014 and 31 December 2020. Individuals' mental disorder diagnosis and Charlson comorbidity and hospital frailty index scores were derived from admission records. Competing risk and cause-specific risk analyses were conducted to examine the impact of having a mental disorder diagnosis on all-cause hospital readmission. Of the 65 861 adults with index CHF admission discharged alive (mean age: 78.6 ± 12.1; 48% female), 19.2% (12 675) had at least one unplanned readmission within 28 days following discharge. Adults with CHF with a mental disorder diagnosis within 12 months had a higher risk of 28 day all-cause unplanned readmission [hazard ratio (HR): 1.21, 95% confidence interval (CI): 1.15-1.27, P-value < 0.001], particularly those with anxiety disorder (HR: 1.49, 95% CI: 1.35-1.65, P-value < 0.001). CHF patients aged ≥85 years (HR: 1.19, 95% CI: 1.11-1.28), having ≥3 other comorbidities (HR: 1.35, 95% CI: 1.25-1.46), and having an intermediate (HR: 1.34, 95% CI: 1.28-1.40) or high (HR: 1.37, 95% CI: 1.27-1.47) frailty score on admission had a higher risk of unplanned readmission. CHF patients with a mental disorder who have ≥3 other comorbidities and an intermediate frailty score had the highest probability of unplanned readmission (29.84%, 95% CI: 24.68-35.73%) after considering other patient-level factors and competing events.
CHF patients who had a mental disorder diagnosis in the past 12 months are more likely to be readmitted compared with those without a mental disorder diagnosis. CHF patients with frailty and a mental disorder have the highest probability of readmission. Addressing mental health care services in CHF patient's discharge plan could potentially assist reduce unplanned readmissions.
降低充血性心力衰竭(CHF)患者的可预防住院率是全球卫生系统面临的一项挑战。与没有精神障碍的 CHF 患者相比,近期或正在患有精神障碍的 CHF 患者可能会有更差的健康结局。本研究旨在研究精神障碍对 CHF 患者 28 天非计划性再入院的影响。
本回顾性队列研究使用了澳大利亚新南威尔士州 2014 年 1 月 1 日至 2020 年 12 月 31 日期间年龄≥18 岁、患有 CHF 入院的成年人的人群水平的公共和私人住院和死亡数据。个体的精神障碍诊断和 Charlson 合并症和医院衰弱指数评分是从入院记录中得出的。进行竞争风险和病因特异性风险分析,以检查在诊断为精神障碍的情况下对全因住院再入院的影响。在 65861 名存活出院的成年患者中(平均年龄:78.6±12.1;48%为女性),19.2%(12675 名)在出院后 28 天内有非计划性再入院。在 12 个月内被诊断为 CHF 合并精神障碍的成年人,28 天全因非计划性再入院的风险更高[风险比(HR):1.21,95%置信区间(CI):1.15-1.27,P 值<0.001],特别是患有焦虑障碍的成年人(HR:1.49,95% CI:1.35-1.65,P 值<0.001)。≥85 岁的 CHF 患者(HR:1.19,95% CI:1.11-1.28)、有≥3 种其他合并症(HR:1.35,95% CI:1.25-1.46)以及入院时处于中度(HR:1.34,95% CI:1.28-1.40)或高度(HR:1.37,95% CI:1.27-1.47)衰弱评分的患者,其非计划性再入院风险更高。考虑到其他患者水平因素和竞争事件后,患有精神障碍且有≥3 种其他合并症和中度衰弱评分的 CHF 患者的非计划性再入院概率最高(29.84%,95% CI:24.68-35.73%)。
在过去 12 个月内被诊断为精神障碍的 CHF 患者比没有精神障碍诊断的患者更有可能再次入院。患有衰弱和精神障碍的 CHF 患者再入院的可能性最高。在 CHF 患者出院计划中解决精神卫生保健服务问题可能有助于减少非计划性再入院。