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儿科重症监护病房中的后部可逆性脑病综合征:病例系列

Posterior Reversible Encephalopathy Syndrome in a Pediatric Intensive Care Unit: A Case Series.

作者信息

Teixeira Beatriz, Gonçalves Vera, Cardoso Ana Lúcia, Ribeiro Fernandes Sofia, Rocha Liliana, Garrido Cristina, Sarmento Alzira

机构信息

Paediatric Department, Centro Materno Infantil do Norte, Centro Hospitalar Universitário de Santo António, Porto, PRT.

Paediatric Department, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.

出版信息

Cureus. 2023 Dec 17;15(12):e50658. doi: 10.7759/cureus.50658. eCollection 2023 Dec.

DOI:10.7759/cureus.50658
PMID:38229800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10790602/
Abstract

Posterior reversible encephalopathy syndrome (PRES) is a reversible clinical-radiographic abnormality. It is characterized by headache, altered consciousness, seizures, and visual disruption, in addition to characteristic white matter edema lesions in the parieto-occipital areas of the brain. Early detection and treatment are crucial to prevent irreversible damage. This paper presents the cases of three patients with PRES with concurrent diagnoses of glomerulonephritis, Guillain-Barré syndrome, and sickle cell disease. All patients experienced systemic hypertension, seizures, and altered consciousness. All patients were admitted to intensive care for decreased level of awareness or requiring invasive mechanical ventilation. Anticonvulsants and antihypertensive therapy were essential. No chronic complications were recorded.

摘要

后部可逆性脑病综合征(PRES)是一种可逆的临床影像学异常。其特征除了脑部顶枕区有特征性的白质水肿病变外,还包括头痛、意识改变、癫痫发作和视觉障碍。早期发现和治疗对于预防不可逆损伤至关重要。本文介绍了3例同时诊断为肾小球肾炎、吉兰-巴雷综合征和镰状细胞病的PRES患者的病例。所有患者均出现全身性高血压、癫痫发作和意识改变。所有患者因意识水平下降或需要有创机械通气而入住重症监护病房。抗惊厥药和抗高血压治疗至关重要。未记录到慢性并发症。

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本文引用的文献

1
Posterior reversible encephalopathy syndrome (PRES): diagnosis and management.后部可逆性脑病综合征(PRES):诊断与治疗。
Pract Neurol. 2022 Jun;22(3):183-189. doi: 10.1136/practneurol-2021-003194. Epub 2022 Jan 19.
2
Posterior Reversible Encephalopathy Syndrome: Clinical Features and Outcome.后部可逆性脑病综合征:临床特征与转归
Front Neurol. 2020 Feb 14;11:71. doi: 10.3389/fneur.2020.00071. eCollection 2020.
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Posterior reversible encephalopathy syndrome in pediatric patients: pathophysiology, diagnosis, and management.
儿童患者的后部可逆性脑病综合征:病理生理学、诊断和治疗。
Leuk Lymphoma. 2019 Oct;60(10):2365-2372. doi: 10.1080/10428194.2019.1594210. Epub 2019 Sep 26.
4
Epidemiology, Comorbidities, and Outcomes of Posterior Reversible Encephalopathy Syndrome in Children in the United States.美国儿童后部可逆性脑病综合征的流行病学、合并症和结局。
Pediatr Neurol. 2020 Feb;103:21-26. doi: 10.1016/j.pediatrneurol.2019.07.007. Epub 2019 Jul 22.
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Two Cases of Guillain-Barré Syndrome Variants Presenting With Dysautonomia.两例以自主神经功能障碍为表现的吉兰-巴雷综合征变异型病例。
Child Neurol Open. 2019 Jun 16;6:2329048X19856778. doi: 10.1177/2329048X19856778. eCollection 2019.
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Posterior reversible encephalopathy syndrome in children with kidney disease.肾病患儿的后部可逆性脑病综合征
Int Urol Nephrol. 2017 Oct;49(10):1793-1800. doi: 10.1007/s11255-017-1684-x. Epub 2017 Aug 23.
7
Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease.镰状细胞病患者的神经系统表现并不总是中风:镰状细胞病中后部可逆性脑病综合征的综述
Pediatr Blood Cancer. 2016 Jun;63(6):983-9. doi: 10.1002/pbc.25932. Epub 2016 Feb 12.
8
Posterior Reversible Encephalopathy Syndrome in Children With Hematologic Malignancies.血液系统恶性肿瘤患儿的后部可逆性脑病综合征
J Child Neurol. 2015 Oct;30(12):1669-75. doi: 10.1177/0883073815578525. Epub 2015 Apr 10.
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Long-term risk of seizures and epilepsy in patients with posterior reversible encephalopathy syndrome.后部可逆性脑病综合征患者癫痫发作和癫痫的长期风险
Epilepsia. 2015 Apr;56(4):564-8. doi: 10.1111/epi.12933. Epub 2015 Feb 18.
10
Life-threatening complications of posterior reversible encephalopathy syndrome in children.儿童后可逆性脑病综合征的危及生命并发症。
Eur J Paediatr Neurol. 2014 Sep;18(5):632-40. doi: 10.1016/j.ejpn.2014.04.014. Epub 2014 Apr 25.