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揭示尼日利亚埃基提州糖尿病负担:一项基于全州家庭的横断面研究的见解

Uncovering the Burden of Diabetes in Ekiti State, Nigeria: Insights From a Statewide, Household-Based, Cross-Sectional Study.

作者信息

Oluwadiya Kehinde S, Raimi Taiwo H, Dada Samuel A, Dele-Ojo Bolade F, Adeoti Adekunle O, Solomon Oluremi O, Amu Eyitope, Awoleke Jacob O, Atiba Samuel A, Babatola Adefunke O, Dada Mobolaji U, Ariyo Olumuyiwa E, Omotayo Adetunji J, Adelekan Ademola O, Ezeani Esu S, Ogundipe Laofe, Akinwunmi Adebowale F, Aina Felix O, Agboola Segun M

机构信息

Department of Surgery, Ekiti State University, Ado Ekiti, NGA.

Department of Medicine, Ekiti State University, Ado Ekiti, NGA.

出版信息

Cureus. 2023 Dec 17;15(12):e50686. doi: 10.7759/cureus.50686. eCollection 2023 Dec.

Abstract

INTRODUCTION

Diabetes mellitus (DM) is an important global public health challenge, and the burden of the disease is huge, particularly in low- and middle-income countries (LMICs), where the majority of people with this condition reside. Undiagnosed DM is more prevalent in LMICs. The aim of this study is to determine the prevalence and associated factors for DM in Ekiti State.

MATERIALS AND METHODS

A cross-sectional, household-based survey using a four-stage multistage sampling design and the World Health Organization (WHO)-STEPS survey manual was conducted from July to September 2020 as a part of the Ekiti State coronavirus disease 2019 (COVID-19) survey. Of the 5,145 sampled households, 4,726 individuals gave consent to participate in the survey. Out of these, 3043 had fasting plasma glucose results available and were included in the analysis.

RESULTS

There were 2257 (74.2%) women and 786 (25.8%) men. The prevalence of DM was 6.5% (6.5% in males and 6.6% in females, P = 0.946). Diabetes was found to be more prevalent among those with a secondary school education or higher (10.9%); employed in the formal sector (13.4%); separated, divorced, or widowed (8.5%); with raised blood pressure (9.3%); and who were aged 30-59 years (all P < 0.05). Multivariable logistic regression showed that age, education, occupation, and hypertension were all positively and significantly associated with an increased risk of DM.

CONCLUSION

The prevalence of DM in Ekiti State is high, and its predictors include advancing age, hypertension, education, and occupation. This calls for scaling up public health interventions for controlling DM, targeting the identified risk factors among the people of Ekiti.

摘要

引言

糖尿病是一项重大的全球性公共卫生挑战,该疾病负担巨大,在低收入和中等收入国家(LMICs)尤为如此,这些国家居住着大多数糖尿病患者。未确诊的糖尿病在低收入和中等收入国家更为普遍。本研究旨在确定埃基蒂州糖尿病的患病率及相关因素。

材料与方法

作为埃基蒂州2019年冠状病毒病(COVID - 19)调查的一部分,于2020年7月至9月采用四阶段多阶段抽样设计和世界卫生组织(WHO)- 逐步调查手册进行了一项基于家庭的横断面调查。在5145个抽样家庭中,4726人同意参与调查。其中,3043人有空腹血糖结果并纳入分析。

结果

有2257名(74.2%)女性和786名(25.8%)男性。糖尿病患病率为6.5%(男性为6.5%,女性为6.6%,P = 0.946)。发现糖尿病在受过中学及以上教育的人群中更为普遍(10.9%);在正规部门就业的人群中(13.4%);分居、离婚或丧偶的人群中(8.5%);血压升高的人群中(9.3%);以及年龄在30 - 59岁的人群中更为普遍(所有P < 0.05)。多变量逻辑回归显示,年龄、教育程度、职业和高血压均与糖尿病风险增加呈正相关且具有显著相关性。

结论

埃基蒂州糖尿病患病率较高,其预测因素包括年龄增长、高血压、教育程度和职业。这就要求扩大公共卫生干预措施以控制糖尿病,针对埃基蒂州人群中已确定的风险因素。

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