Kim Chaewon, Na Yoojin, Lee Sanghee, Park Jung Yoon, Chung Youn-Jee, Song Jaeyen, Kim Mee-Ran
Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Menopausal Med. 2023 Dec;29(3):85-91. doi: 10.6118/jmm.23016.
The treatment strategy for postmenopausal symptoms resulting from estrogen deficiency in breast cancer survivors receiving endocrine therapy should differ from that in normal women. Several nonhormonal pharmacological therapies can be used to treat vasomotor symptoms. Cognitive-behavioral therapy can help alleviate psychophysiological symptoms, including depression and sleep disorders. Topical vaginal estrogen and moisturizers may aid in treating genitourinary symptoms. Additionally, chronic conditions must be individually managed. Prevention of osteoporosis should always be included in the management, and physicians should be alert to possible cardiovascular risk and cognitive function changes.
接受内分泌治疗的乳腺癌幸存者因雌激素缺乏导致的绝经后症状的治疗策略应与正常女性不同。几种非激素药物疗法可用于治疗血管舒缩症状。认知行为疗法有助于缓解心理生理症状，包括抑郁和睡眠障碍。局部阴道雌激素和保湿剂可能有助于治疗泌尿生殖系统症状。此外，慢性病必须进行个体化管理。骨质疏松症的预防应始终纳入管理之中，医生应警惕可能的心血管风险和认知功能变化。
