Zhang Ziyu, Zhang Yuhua, Tian Yang, Fu Zhinan, Guo Jiangtao, He Guofeng, Li Li, Zhao Fang, Guo Xuhong
State Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
Jiangsu Feymer Technology Co., Ltd., Zhangjiagang 215613, China.
Polymers (Basel). 2023 Nov 30;15(23):4576. doi: 10.3390/polym15234576.
Nanosized spherical polyelectrolyte brushes (SPBs) are ideal candidates for the preparation of nanometal catalysts, protein separation, and medical diagnostics. Until now, SPBs have been synthesized by photo-emulsion polymerization in a batch reactor, which remains challenging to scale up. This paper reports a successful continuous preparation of SPBs by photo-emulsion polymerization in a self-made microreactor. The effects of residence time, monomer concentration, and feed ratios on the conversion of monomers and SPB structures are systematically investigated by dynamic lighting scattering and transmission electron microscopy. Poly(acrylic acid) (PAA) SPBs obtained in a microreactor exhibiting a narrow size distribution with a short reaction time are very effective in inhibiting the calcium carbonate scale and are comparable to those produced in a batch reactor. This work confirms the feasibility of continuous preparation and scaled-up production of SPBs.
纳米级球形聚电解质刷（SPB）是制备纳米金属催化剂、蛋白质分离和医学诊断的理想候选材料。到目前为止，SPB是通过间歇式反应器中的光乳液聚合合成的，这种方法扩大规模仍然具有挑战性。本文报道了在自制微反应器中通过光乳液聚合成功连续制备SPB。通过动态光散射和透射电子显微镜系统地研究了停留时间、单体浓度和进料比例对单体转化率和SPB结构的影响。在微反应器中获得的聚（丙烯酸）（PAA）SPB在短反应时间内具有窄尺寸分布，在抑制碳酸钙垢方面非常有效，与间歇式反应器中生产的产品相当。这项工作证实了连续制备和扩大规模生产SPB的可行性。
