DBS&H, CEME, National University of Sciences and Technology, Islamabad 44000, Pakistan.
COMSATS University, Islamabad, 44000, Pakistan.
Sci Rep. 2024 Jan 17;14(1):1475. doi: 10.1038/s41598-024-51848-4.
The magnetic force effects and differently shaped nano-particles in diverging tapering arteries having stenoses are being studied in current research via blood flow model. There hasn't been any research done on using metallic nanoparticles of different shapes with water as the base fluid. A radially symmetric but axially non-symmetric stenosis is used to depict the blood flow. Another significant aspect of our research is the study of symmetrical distribution of wall shearing stresses in connection with resistive impedance, as well as the rise of these quantities with the progression of stenosis. Shaping nanoparticles in accordance with the understanding of blood flow in arteries offers numerous possibilities for improving drug delivery, targeted therapies, and diagnostic imaging in the context of cardiovascular and other vascular-related diseases. Exact solutions for different flow quantities namely velocity, temperature, resistance impedance, boundary shear stress, and shearing stress at the stenosis throat, have been assessed. For various parameters of relevance for Cu-water, the graphical results of several types of tapered arteries (i.e. diverging tapering) have been explored.
当前研究通过血流模型研究了具有狭窄的发散渐缩动脉中的磁力效应和不同形状的纳米粒子。尚未有任何关于使用不同形状的金属纳米粒子和水作为基液的研究。使用径向对称但轴向非对称的狭窄来描述血流。我们研究的另一个重要方面是研究与电阻抗有关的壁剪切应力的对称分布,以及随着狭窄程度的增加这些量的增加。根据对动脉血流的理解来塑造纳米粒子,为改善心血管和其他血管相关疾病背景下的药物输送、靶向治疗和诊断成像提供了多种可能性。评估了不同流动量(即速度、温度、电阻抗、边界剪切应力和狭窄处的剪切应力)的精确解。针对与 Cu-水相关的各种参数,已经研究了几种类型的锥形动脉(即发散渐缩)的图形结果。