Swapnil Zaman, Wang Jiankun, He Kexin, Liu Li, Fan Zhining
Digestive Endoscopy and General Surgeri, The First Affiliated Hospital with Nanjing Medical University.
Digestive Endoscopy and General Surgery, The First Affiliated Hospital with Nanjing Medical University, China.
Rev Esp Enferm Dig. 2025 Feb;117(2):118-119. doi: 10.17235/reed.2024.10203/2023.
Esophageal stenosis after ESD has been recorded high for large-scale esophageal lesion. Risk factors for increasing the occurrence of stenosis includes long type lesions, lesions infiltrating into the muscularis mucosa and muscular layer injury. In this case, postoperative stricture of the patient was highly likely occurred. Smectite is a mucosal protective agent that can resist external stimuli, promote wound healing, and reduce inflammatory factors. Therefore, it can effectively prevent the formation of scars on wounds. This study was carried out in humans for the first time and was successful. In conclusion, endoscopic spraying of smectite may be effective and safe in preventing esophageal stenosis after ESD with large non-circumferential lesions.
对于大面积食管病变，ESD术后食管狭窄的发生率已被记录为很高。增加狭窄发生的危险因素包括长型病变、浸润至黏膜肌层的病变以及肌层损伤。在这种情况下，该患者术后很可能发生了狭窄。蒙脱石是一种黏膜保护剂，可抵抗外部刺激、促进伤口愈合并减少炎症因子。因此，它可有效防止伤口形成瘢痕。本研究首次在人体中进行且取得了成功。总之，对于非环周性大病变的ESD术后，内镜下喷洒蒙脱石在预防食管狭窄方面可能有效且安全。
