Service de Cardiologie, Centre Hospitalier Universitaire Trousseau, Faculté de Médecine, Université François Rabelais, Tours, France.
Curr Heart Fail Rep. 2024 Feb;21(1):33-42. doi: 10.1007/s11897-023-00641-x. Epub 2024 Jan 18.
Wearable cardioverter defibrillators (WCDs) have been developed as a temporary measure for protecting patients at risk for sudden cardiac death that do not meet the indication for implantable cardioverter defibrillator (ICD), most notably in the early stages of heart failure with reduced ejection fraction before reassessment of their left ventricular ejection fraction. In this review, we report available evidence in the literature and guidelines regarding WCD use in order to try to define the role WCDs may have in heart failure.
In the last decade, most observational studies found WCDs to be both safe and effective in terminating ventricular arrhythmias in various indications, mostly centered around heart failure with reduced ejection fraction. The only available randomized controlled trial using WCD did not however show a benefit on patients' survival. Hence, recent guidelines only recommended its use in limited indications. Recent data also suggest a possible interest of WCD in monitoring patients, a finding that may prove useful in the context of new-onset heart failure. Data regarding WCD benefit is scarce, and definitive conclusions on its utility are hard to draw. In the context of heart failure, and particularly new-onset heart failure, WCD might find a role in a global comprehensive management of the disease, both acting as an educational tool, a monitoring tool, and, most importantly, a safe and effective tool in preventing sudden cardiac death. The low level of evidence however invites caution, and the decision of prescribing a WCD needs to be individualized and thoroughly discussed with the patient whose compliance is key with this device.
可穿戴式除颤器 (WCD) 的开发是作为一种临时措施,用于保护有发生心源性猝死风险但不符合植入式心律转复除颤器 (ICD) 适应证的患者,尤其是在射血分数降低的心力衰竭早期阶段,在重新评估其左心室射血分数之前。在本综述中,我们报告了文献和指南中关于 WCD 使用的现有证据,以尝试确定 WCD 在心力衰竭中的作用。
在过去十年中,大多数观察性研究发现 WCD 在各种适应证中都能安全有效地终止室性心律失常,主要集中在射血分数降低的心力衰竭。然而,唯一一项使用 WCD 的随机对照试验并未显示出对患者生存的益处。因此,最近的指南仅建议在有限的适应证中使用 WCD。最近的数据还表明 WCD 可能对监测患者有一定的益处,这一发现可能在新发心力衰竭的情况下证明是有用的。关于 WCD 益处的数据很少,很难得出其实际应用的明确结论。在心力衰竭,特别是新发心力衰竭的情况下,WCD 可能在疾病的全面综合管理中发挥作用,既是一种教育工具,也是一种监测工具,最重要的是,它是预防心源性猝死的一种安全有效的工具。然而,证据水平较低,需要谨慎,开处方 WCD 的决定需要个体化,并与患者进行彻底讨论,患者的依从性是使用该设备的关键。