Nuutinen J, Holopainen E, Haahtela T, Ruoppi P, Silvasti M
Rhinology. 1986 Dec;24(4):265-9.
The effects of a special balanced physiological saline on nasal symptoms of 93 patients with chronic rhinitis were studied. The main diagnoses of the patients were allergic rhinitis, atrophic rhinitis and ozaena, rhinitis sicca, chronic sinusitis, nasal polyposis and postoperative condition after nasal surgery. The tested solution was administered by a simple metered dose pump. 85 (91%) of the patients reported beneficial effects of the tested solution on nasal symptoms. In addition, 22 (71%) of those patients who used continuous anti-allergic medication, mainly intranasal steroids, reported that the tested solution improved the efficacy of their ordinary drug. So the tested solution proved to be beneficial in humidifying atrophic or otherwise dry mucosa, douching crusty nose and as adjuvant therapy in the treatment of allergic rhinitis.
研究了一种特殊的平衡生理盐溶液对93例慢性鼻炎患者鼻部症状的影响。患者的主要诊断包括变应性鼻炎、萎缩性鼻炎和臭鼻症、干燥性鼻炎、慢性鼻窦炎、鼻息肉以及鼻部手术后的状况。受试溶液通过简易定量泵给药。85例(91%)患者报告受试溶液对鼻部症状有有益作用。此外,在主要使用鼻内类固醇等持续抗变态反应药物的患者中,有22例(71%)报告受试溶液提高了其常用药物的疗效。因此,受试溶液在湿润萎缩性或其他干燥的黏膜、冲洗结痂的鼻腔以及作为变应性鼻炎治疗的辅助疗法方面被证明是有益的。