Josa-Culleré Alícia, Basagaña Xavier, Koch Sarah, Arbillaga-Etxarri Ane, Balcells Eva, Bosch de Basea Magda, Celorrio Nuria, Foraster Maria, Rodriguez-Roisin Robert, Marin Alicia, Peralta Gabriela P, Rodríguez-Chiaradia Diego A, Simonet Pere, Torán-Monserrat Pere, Vall-Casas Pere, Garcia-Aymerich Judith
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
Deusto Physical TherapIker, Physical Therapy Department, Faculty of Health Sciences, University of Deusto, Donostia-San Sebastián, Spain.
Environ Res. 2024 Apr 15;247:118195. doi: 10.1016/j.envres.2024.118195. Epub 2024 Jan 16.
Patients with chronic obstructive pulmonary disease (COPD) accumulate low levels of physical activity. How environmental factors affect their physical activity in the short-term is uncertain.
to assess the short-term effects of air pollution and weather on physical activity levels in COPD patients.
This multi-center panel study assessed 408 COPD patients from Catalonia (Spain). Daily physical activity (i.e., steps, time in moderate-to-vigorous physical activity (MVPA), locomotion intensity, and sedentary time) was recorded in two 7-day periods, one year apart, using the Dynaport MoveMonitor. Air pollution (nitrogen dioxide (NO), particulate matter below 10 μm (PM) and a marker of black carbon (absorbance of PM: PM), and weather (average and maximum temperature, and rainfall) were estimated the same day (lag zero) and up to 5 days prior to each assessment (lags 1-5). Mixed-effect distributed lag linear regression models were adjusted for age, sex, weekday, public holidays, greenness, season, and social class, with patient and city as random effects.
Patients (85% male) were on average (mean ± SD) 68 ± 9 years old with a post-bronchodilator forced expiratory volume in 1 s (FEV) of 57 ± 18% predicted. Higher NO, PM and PM levels at lag four were associated with fewer steps, less time in MVPA, reduced locomotion intensity, and longer sedentary time (e.g., coefficient (95% CI) of -60 (-105, -15) steps per 10 μg/m increase in NO). Higher average and maximum temperatures at lag zero were related to more steps and time in MVPA, and less sedentary time (e.g., +85 (15, 154) steps per degree Celsius). Higher rainfall at lag zero was related to fewer steps and more sedentary time.
Air pollution affects the amount and intensity of physical activity performed on the following days in COPD patients, whereas weather affects the amount of physical activity performed on the same day.
慢性阻塞性肺疾病（COPD）患者的身体活动水平较低。环境因素如何在短期内影响他们的身体活动尚不确定。
评估空气污染和天气对COPD患者身体活动水平的短期影响。
这项多中心小组研究评估了来自加泰罗尼亚（西班牙）的408名COPD患者。使用Dynaport MoveMonitor在相隔一年的两个7天时间段内记录每日身体活动情况（即步数、中度至剧烈身体活动（MVPA）时间、运动强度和久坐时间）。在每次评估当天（滞后零天）以及之前多达5天（滞后1 - 5天）估算空气污染（二氧化氮（NO）、10微米以下颗粒物（PM）以及黑碳标志物（PM吸光度：PM））和天气（平均温度、最高温度和降雨量）。混合效应分布滞后线性回归模型针对年龄、性别、工作日、公共假日、绿化程度、季节和社会阶层进行了调整，并将患者和城市作为随机效应。
患者（85%为男性）平均年龄（均值±标准差）为68±9岁，支气管扩张剂使用后1秒用力呼气量（FEV）为预测值的57±18%。滞后四天时较高的NO、PM和PM水平与步数减少、MVPA时间减少、运动强度降低以及久坐时间延长相关（例如，NO每增加10μg/m，系数（95%置信区间）为 -60（-105，-15）步）。滞后零天较高的平均温度和最高温度与更多步数、MVPA时间以及更少久坐时间相关（例如，每摄氏度增加85（15，154）步）。滞后零天较高的降雨量与步数减少和更多久坐时间相关。
空气污染会影响COPD患者在接下来几天的身体活动量和强度，而天气会影响同一天的身体活动量。
