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Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation.

作者信息

Pittet Laure F, Noble Christie C A, Messina Nicole L, Curtis Nigel

机构信息

Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.

Murdoch Children's Research Institute, Parkville, Victoria, Australia.

出版信息

Nat Rev Immunol. 2024 Feb;24(2):83-84. doi: 10.1038/s41577-024-00992-z.

DOI:10.1038/s41577-024-00992-z
PMID:38238441
Abstract
摘要

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本文引用的文献

1
Interpreting the Results of Trials of BCG Vaccination for Protection Against COVID-19.解读卡介苗（BCG）疫苗接种预防 COVID-19 临床试验结果。
J Infect Dis. 2023 Nov 11;228(10):1467-1478. doi: 10.1093/infdis/jiad316.
2
Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers.BCG 疫苗预防医护人员感染 COVID-19 的随机临床试验
N Engl J Med. 2023 Apr 27;388(17):1582-1596. doi: 10.1056/NEJMoa2212616.
3
The effect of BCG vaccination on infection and antibody levels against SARS-CoV-2-The results of ProBCG: a multicenter randomized clinical trial in Brazil.
训练有素的免疫在健康与疾病中的作用。
Curr Cardiol Rep. 2025 Jan 13;27(1):18. doi: 10.1007/s11886-024-02167-7.
4
BCG vaccination of healthcare workers for protection against COVID-19: 12-month outcomes from an international randomised controlled trial.医护人员接种卡介苗以预防 COVID-19：一项国际随机对照试验的 12 个月结果。
J Infect. 2024 Oct;89(4):106245. doi: 10.1016/j.jinf.2024.106245. Epub 2024 Aug 8.
5
Bacille Calmette-Guérin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial.卡介苗接种预防成人发热和呼吸道疾病（BRACE）：一项随机对照3期试验的次要结果
EClinicalMedicine. 2024 May 13;72:102616. doi: 10.1016/j.eclinm.2024.102616. eCollection 2024 Jun.
BCG 疫苗接种对感染和针对 SARS-CoV-2 的抗体水平的影响——ProBCG 研究的结果：巴西的一项多中心随机临床试验。
Int J Infect Dis. 2023 May;130:8-16. doi: 10.1016/j.ijid.2023.02.014. Epub 2023 Feb 24.
4
Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial.卡介苗疫苗预防有合并症的老年人群 COVID-19 和其他呼吸道感染：一项随机对照试验。
Clin Microbiol Infect. 2023 Jun;29(6):781-788. doi: 10.1016/j.cmi.2023.01.019. Epub 2023 Feb 2.
5
Efficacy of Bacillus Calmette-Guérin (BCG) Vaccination in Reducing the Incidence and Severity of COVID-19 in High-Risk Population (BRIC): a Phase III, Multi-centre, Quadruple-Blind Randomised Control Trial.卡介苗（BCG）接种对降低高危人群（BRIC）中新冠病毒疾病（COVID-19）发病率和严重程度的疗效：一项III期、多中心、四盲随机对照试验
Infect Dis Ther. 2022 Dec;11(6):2205-2217. doi: 10.1007/s40121-022-00703-y. Epub 2022 Oct 15.
6
Multiple BCG vaccinations for the prevention of COVID-19 and other infectious diseases in type 1 diabetes.多次接种卡介苗预防 1 型糖尿病患者感染 COVID-19 和其他传染病。
Cell Rep Med. 2022 Sep 20;3(9):100728. doi: 10.1016/j.xcrm.2022.100728. Epub 2022 Aug 15.
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Front Immunol. 2022 Jul 5;13:873067. doi: 10.3389/fimmu.2022.873067. eCollection 2022.
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EClinicalMedicine. 2022 Jun;48:101414. doi: 10.1016/j.eclinm.2022.101414. Epub 2022 May 12.
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Clin Microbiol Infect. 2022 Sep;28(9):1278-1285. doi: 10.1016/j.cmi.2022.04.009. Epub 2022 Apr 28.
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Front Immunol. 2022 Mar 22;13:841868. doi: 10.3389/fimmu.2022.841868. eCollection 2022.