Kubiszewski Kacper, Chapman Rachel W, Piazza Yelena, Patel Dhruv, Neychev Vladimir
Medical School, University of Central Florida College of Medicine, Orlando, USA.
Pathology, University of Central Florida College of Medicine, Orlando, USA.
Cureus. 2023 Dec 19;15(12):e50799. doi: 10.7759/cureus.50799. eCollection 2023 Dec.
Patients who present with nausea, vomiting, constipation, and abdominal pain typically undergo workups for small bowel obstruction (SBO). SBO is commonly caused by mechanical obstruction due to adhesions, inflammatory conditions, or malignancies. Hypothyroidism is primarily associated with decreased basal metabolic rate and rarely, in severe cases, gastrointestinal motility dysfunction. We report a case of a 44-year-old man who presented to the emergency department with abdominal pain, nausea, and vomiting. The workup, including computed tomography, showed a small bowel feces sign, highly suspicious for a mechanical SBO. His past medical history was significant for a poorly controlled hypothyroidism due to Hashimoto's thyroiditis with a markedly elevated thyroid stimulating hormone (TSH) level. He had no prior surgical history, and his family history was significant for a suspected inflammatory bowel disease (IBD) in his son. The patient failed initial resuscitative nonoperative management and underwent exploratory laparoscopy that revealed diffusely dilated small bowel loops with no obvious cause of mechanical obstruction. Inflammatory markers for IBD were found to be negative, and the patient's gastrointestinal motility gradually improved with daily intravenous levothyroxine.
出现恶心、呕吐、便秘和腹痛症状的患者通常会接受小肠梗阻(SBO)的检查。SBO通常由粘连、炎症性疾病或恶性肿瘤等机械性梗阻引起。甲状腺功能减退主要与基础代谢率降低相关,在严重情况下,很少会出现胃肠动力功能障碍。我们报告一例44岁男性患者,他因腹痛、恶心和呕吐到急诊科就诊。包括计算机断层扫描在内的检查显示有小肠粪石征,高度怀疑为机械性SBO。他既往有因桥本甲状腺炎导致甲状腺功能减退控制不佳的病史,促甲状腺激素(TSH)水平明显升高。他既往无手术史,家族史中其儿子疑似患有炎症性肠病(IBD)。患者初始复苏性非手术治疗失败,接受了 exploratory laparoscopy,结果显示小肠袢广泛扩张,无明显机械性梗阻原因。IBD的炎症标志物检测为阴性,患者通过每日静脉注射左甲状腺素,胃肠动力逐渐改善。 (注:“exploratory laparoscopy”直译为“探索性腹腔镜检查”,结合语境这里可能是指腹腔镜探查术之类的操作,不太确定准确的医学术语,暂保留英文未翻译更准确的表述)