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骶尾部脊索瘤。60例患者的临床放射学研究。

Sacrococcygeal chordoma. A clinicoradiological study of 60 patients.

作者信息

Smith J, Ludwig R L, Marcove R C

出版信息

Skeletal Radiol. 1987;16(1):37-44. doi: 10.1007/BF00349926.

Abstract

Sixty patients with sacrococcygeal chordoma, who were seen at this center between 1946 and 1985, were studied with particular attention to the radiographic findings. This study was undertaken because of the large number of these cases and comparison was made between the plain films available in 39 patients and the computed tomography CT studies in 22. Bone destruction was found in 78% on plain films but in 90% on CT. A soft tissue mass was identified in plain films in 60% but in 90% on CT. Calcific debris was found in plain films in 44% but in 87% on CT. Mostly the debris consisted of coarse irregular fragments and probably represented sequestrated necrotic bone. Myelography was performed in only 15 patients. Angiography was studied in 10 cases. Of the 60 patients 88% underwent surgical resection. The tumor recurred in 80% and in only 20% was there no evidence of recurrence. Distant metastases occurred in 24% of patients. Fifty percent survived 5 years; 28% survived 10 years; mean survival 7.5 years.

摘要

1946年至1985年间,本中心收治了60例骶尾部脊索瘤患者,对其影像学表现进行了特别研究。开展这项研究是因为此类病例数量众多,并对39例患者的平片与22例患者的计算机断层扫描(CT)研究结果进行了比较。平片显示78%的患者存在骨质破坏,而CT显示为90%。平片显示60%的患者有软组织肿块,CT显示为90%。平片显示44%的患者有钙化碎片,CT显示为87%。这些碎片大多由粗大不规则的碎块组成,可能代表了分离的坏死骨。仅15例患者进行了脊髓造影。10例患者进行了血管造影研究。60例患者中,88%接受了手术切除。80%的患者肿瘤复发,只有20%没有复发迹象。24%的患者发生远处转移。50%的患者存活了5年;28%的患者存活了10年;平均生存期为7.5年。

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