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T细胞原淋巴细胞白血病：新型治疗时代的流行病学与生存趋势

T-cell prolymphocytic leukemia: Epidemiology and survival trends in the era of novel treatments.

作者信息

Vardell Victoria A, Ermann Daniel A, Fitzgerald Lindsey, Shah Harsh, Hu Boyu, Stephens Deborah M

机构信息

Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.

Division of Hematology and Hematologic Malignancies, University of North Carolina, Chapel Hill, North Carolina, USA.

出版信息

Am J Hematol. 2024 Mar;99(3):494-496. doi: 10.1002/ajh.27205. Epub 2024 Jan 19.

DOI:10.1002/ajh.27205
PMID:38240336
Abstract

Survival remains poor for T-cell prolymphocytic leukemia, though treatment in recent years, associated with access to novel therapies, and management at academic medical centers is associated with improved outcomes. There remains a critical need to improve the available treatment options for this population, and access to specialized academic medical centers, comprehensive supportive care, clinical trials, and early palliative care remains essential for T-PLL patients.

摘要

T细胞幼淋巴细胞白血病的生存率仍然很低，尽管近年来的治疗与获得新疗法有关，且在学术医疗中心进行管理与改善预后相关。对于这一人群，仍然迫切需要改善现有的治疗选择，对于T-PLL患者而言，进入专业学术医疗中心、获得全面的支持性护理、参与临床试验以及早期姑息治疗仍然至关重要。

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