Rosin I V
Ter Arkh. 1986;58(12):100-2.
During expeditions clinical and roentgenological symptoms were studied in 129 persons aged under 25 and 53 persons aged over 25 with threatened Kashin-Bek disease and afflicted with it, who were followed-up. Observation over time showed that preclinical signs in the form of x-ray morphological changes in the hand joints were the following: a niche in the fifth finger middle phalanx metaphysis or (less frequently) in the thumb ungual phalanx and foci of epiphyseal outer resorption. The initial characteristic clinical signs of the disease were deformity of the proximal interphalangeal joints of the II-V fingers and brachydactyly of the fifth finger. Early clinical and roentgenological signs of Kashin-Bek disease were specified in the time course of the study improving thus the diagnosis and follow-up of such patients.
在考察期间，对129名25岁以下和53名25岁以上患有潜在卡辛 - 贝克病及已患病的人员进行了临床和X线症状研究，并对他们进行了随访。随着时间的观察发现，手部关节X线形态学变化形式的临床前期体征如下：第五指中节指骨干骺端有龛影，或（较少见）拇指末节指骨有龛影，以及骨骺外侧吸收灶。该病最初的典型临床体征为第II - V指近端指间关节畸形和第五指短指畸形。在研究过程中明确了卡辛 - 贝克病的早期临床和X线体征，从而改善了此类患者的诊断和随访情况。
