Department of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Department of Biomedical Engineering, University of Utah, 36 S Wasatch Dr., Salt Lake City, UT, 84112, USA.
Curr Osteoporos Rep. 2024 Feb;22(1):44-55. doi: 10.1007/s11914-023-00845-z. Epub 2024 Jan 20.
Musculoskeletal imaging serves a critical role in clinical care and orthopaedic research. Image-based modeling is also gaining traction as a useful tool in understanding skeletal morphology and mechanics. However, there are fewer studies on advanced imaging and modeling in pediatric populations. The purpose of this review is to provide an overview of recent literature on skeletal imaging modalities and modeling techniques with a special emphasis on current and future uses in pediatric research and clinical care.
While many principles of imaging and 3D modeling are relevant across the lifespan, there are special considerations for pediatric musculoskeletal imaging and fewer studies of 3D skeletal modeling in pediatric populations. Improved understanding of bone morphology and growth during childhood in healthy and pathologic patients may provide new insight into the pathophysiology of pediatric-onset skeletal diseases and the biomechanics of bone development. Clinical translation of 3D modeling tools developed in orthopaedic research is limited by the requirement for manual image segmentation and the resources needed for segmentation, modeling, and analysis. This paper highlights the current and future uses of common musculoskeletal imaging modalities and 3D modeling techniques in pediatric orthopaedic clinical care and research.
肌肉骨骼成像在临床护理和骨科研究中起着至关重要的作用。基于图像的建模也作为一种理解骨骼形态和力学的有用工具而受到关注。然而，关于儿科人群的高级成像和建模的研究较少。本文的目的是提供骨骼成像方式和建模技术的最新文献综述，特别强调在儿科研究和临床护理中的当前和未来用途。
虽然成像和三维建模的许多原则在整个生命周期中都具有相关性，但儿科肌肉骨骼成像有特殊考虑因素，并且在儿科人群中对三维骨骼建模的研究较少。在健康和患病患者中，对儿童时期骨骼形态和生长的深入了解可能为儿科发病骨骼疾病的病理生理学和骨骼发育的生物力学提供新的见解。在骨科研究中开发的 3D 建模工具的临床转化受到手动图像分割的要求以及分割、建模和分析所需的资源的限制。本文强调了常见的肌肉骨骼成像方式和 3D 建模技术在儿科骨科临床护理和研究中的当前和未来用途。
