选择液体以降低肾移植后儿童急性电解质紊乱的风险。

Choosing fluids to reduce the risks of acute electrolyte disturbances in children after a kidney transplant.

机构信息

Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.

Child and Adolescent Renal Service, Queensland Children's Hospital, Brisbane, Queensland, Australia; Children's Health Queensland Clinical Unit, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.

出版信息

Kidney Int. 2024 Feb;105(2):247-250. doi: 10.1016/j.kint.2023.11.015.

DOI:10.1016/j.kint.2023.11.015

PMID:38245215

Abstract

Intravenous (i.v.) fluid therapy is critically important in pediatric kidney transplantation. Because of the high volumes given perioperatively, transplant recipients can develop significant electrolyte abnormalities depending on the types of fluids used. Current practices in pediatric transplantation aim to balance risks of hyponatremia from traditionally used hypotonic fluids, such as 0.45% sodium chloride, against hyperchloremia and acidosis associated with isotonic 0.9% sodium chloride. Using the balanced solution Plasma-Lyte 148 as an alternative might mitigate these risks.

摘要

静脉（i.v.）液体疗法在小儿肾移植中至关重要。由于围手术期给予的高容量，移植受者可能会根据使用的液体类型出现明显的电解质异常。儿科移植的当前实践旨在平衡传统使用的低渗液（如 0.45%氯化钠）引起的低钠血症风险，以及与等渗 0.9%氯化钠相关的高氯血症和酸中毒风险。使用平衡溶液 Plasma-Lyte 148 作为替代可能会降低这些风险。