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增强非酒精性脂肪肝检测:计算机断层扫描图像分析及形态学膨胀降噪。

Enhanced non-alcoholic fatty liver detection: Computed tomography scan image analysis and noise reduction with morphological dilation.

机构信息

Electronics and Communication Engineering, Pragati Engineering College, Surampalem, Kakinada 533437, Andhra Pradesh, India.

出版信息

Arab J Gastroenterol. 2024 Feb;25(1):1-12. doi: 10.1016/j.ajg.2023.07.005. Epub 2024 Jan 19.

Abstract

Non-alcoholic fatty liver disease (NAFLD) is characterized by accumulation of fat in the liver cells caused by means other than alcohol consumption. It is one of the most common chronic liver diseases worldwide and can lead to severe conditions, such as cirrhosis and liver cancer. NAFLD is often associated with other metabolic disorders, such as obesity and diabetes, and is closely related to lifestyle factors, such as diet and physical activity [1]. The diagnosis as well as management of NAFLD are complex and involve a multidisciplinary approach. The available treatment options include lifestyle modifications, pharmacological interventions, and in severe cases, liver transplantation. The increasing prevalence of NAFLD highlights the urgent requirement of effective prevention and management strategies. This disease is a growing health concern in India, given the rise in the incidence of obesity and diabetes. According to a study published in the Journal of Clinical and Experimental Hepatology in 2020, the prevalence of NAFLD in India is estimated to be between 9% and 32%. In accordance with the research population and diagnostic criteria employed, a study published in the Indian Journal of Gastroenterology in 2019 found that the prevalence of NAFLD in India ranged from 9.6% to 32.3% [2]. The same study also revealed that the prevalence of non-alcoholic steatohepatitis (NASH), a highly severe form of NAFLD, ranged from 1.5% to 8.4%. These statistics highlight the need for increased awareness and preventive measures to manage the growing burden of NAFLD in India.

摘要

非酒精性脂肪性肝病(NAFLD)的特征是肝脏细胞内脂肪堆积,其原因并非酒精摄入。这是全球最常见的慢性肝病之一,可导致严重后果,如肝硬化和肝癌。NAFLD 常与其他代谢紊乱相关,如肥胖和糖尿病,且与生活方式因素密切相关,如饮食和体育活动[1]。NAFLD 的诊断和管理较为复杂,涉及多学科方法。现有的治疗选择包括生活方式改变、药物干预,以及在严重情况下进行肝移植。NAFLD 的发病率不断上升,突显了制定有效预防和管理策略的迫切需求。鉴于肥胖症和糖尿病发病率的上升,印度的 NAFLD 患病率不断增加,成为一个日益严重的健康问题。根据 2020 年《临床与实验肝脏病学杂志》上发表的一项研究,印度的 NAFLD 患病率估计在 9%至 32%之间[2]。根据研究人群和采用的诊断标准,2019 年《印度胃肠病学杂志》上发表的一项研究发现,印度的 NAFLD 患病率在 9.6%至 32.3%之间[3]。同一研究还表明,非酒精性脂肪性肝炎(NASH)的患病率(NAFLD 的一种严重形式)在 1.5%至 8.4%之间。这些统计数据强调了需要提高认识和采取预防措施,以应对印度不断增加的 NAFLD 负担。

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