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加拿大择期痔切除术的成本-效用研究。

A cost-utility study of elective haemorrhoidectomies in Canada.

机构信息

Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.

Department of Colorectal Surgery, St Paul's Hospital, Vancouver, British Columbia, Canada.

出版信息

Colorectal Dis. 2024 Mar;26(3):527-533. doi: 10.1111/codi.16867. Epub 2024 Jan 21.

DOI:10.1111/codi.16867
PMID:38247259
Abstract

AIM

The aim was to estimate the 10-year cost-utility of haemorrhoidectomy surgery with preference-based measures of health using Canadian health utility measures and costs.

METHODS

Patients undergoing elective haemorrhoidectomies by general and colorectal surgeons in British Columbia, Vancouver, between September 2015 and November 2022, completed preoperatively and postoperatively the EuroQol five-dimension five-level health-related quality of life questionnaire (EQ-5D-5L). Quality-adjusted life years (QALYs) attributable to surgery were calculated by discounting preoperative and postoperative health utility values derived from the EQ-5D-5L. Costs were measured from a health system perspective which incorporated costs of hospital stay and specialists' fees. Results are presented in 2021 Canadian dollars.

RESULTS

Of 94 (47%) patients who completed both the preoperative and postoperative questionnaires, the mean gain in QALYs 10 years after surgery was 1.0609, assuming a 3.5% annual discounting rate. The average cost of the surgery was $3166. The average cost per QALY was $2985 when benefits of the surgery were assumed to accrue for 10 years. The cost per QALY was higher for women ($3821) compared with men ($2485). Participants over the age of 70 had the highest cost per QALY ($8079/QALY).

CONCLUSIONS

Haemorrhoidectomies have been associated with significant gains in health status and are inexpensive relative to the associated gains in quality of life based on patients' perspectives of their improvement in health and well-being.

摘要

目的

使用加拿大健康效用测量值和成本,通过偏好健康测量值来评估痔切除术的 10 年成本效用。

方法

2015 年 9 月至 2022 年 11 月,不列颠哥伦比亚省温哥华的普通外科医生和结直肠外科医生对接受择期痔切除术的患者进行了研究,患者在术前和术后完成了欧洲五维健康量表 5 级问卷(EQ-5D-5L)。通过折扣术前和术后来自 EQ-5D-5L 的健康效用值来计算手术归因的质量调整生命年(QALY)。从健康系统的角度衡量成本,其中包括住院和专家费用。结果以 2021 加元表示。

结果

在完成术前和术后问卷调查的 94 名(47%)患者中,假设每年贴现率为 3.5%,术后 10 年 QALY 的平均增益为 1.0609。手术的平均成本为 3166 加元。当手术的收益假设持续 10 年时,手术的每 QALY 成本为 2985 加元。与男性(2485 加元)相比,女性(3821 加元)的每 QALY 成本更高。年龄超过 70 岁的参与者的每 QALY 成本最高(8079 加元/QALY)。

结论

从患者对健康改善和幸福感的角度来看,痔切除术与健康状况的显著改善相关,且相对于生活质量的提高而言,成本较低。

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