Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padova, Italy.
Department of Cardiothoracic Surgery, University of Louisville, Louisville, KY 40292, USA.
Med Sci (Basel). 2024 Jan 11;12(1):6. doi: 10.3390/medsci12010006.
Vein grafts are the most used conduits in coronary artery bypass grafting (CABG), even though many studies have suggested their lower patency compared to arterial alternatives. We have reviewed the techniques and technologies that have been investigated over the years with the aim of improving the quality of these conduits. We found that preoperative and postoperative optimal medical therapy and no-touch harvesting techniques have the strongest evidence for optimizing vein graft patency. On the other hand, the use of venous external support, endoscopic harvesting, vein preservation solution and anastomosis, and graft configuration need further investigation. We have also analyzed strategies to treat vein graft failure: when feasible, re-doing the CABG and native vessel primary coronary intervention (PCI) are the best options, followed by percutaneous procedures targeting the failed grafts.
静脉移植物是冠状动脉旁路移植术 (CABG) 中最常用的移植物,尽管许多研究表明与动脉替代物相比,其通畅率较低。我们回顾了多年来研究的技术和方法,旨在提高这些移植物的质量。我们发现,术前和术后的最佳药物治疗和非接触式采集技术对优化静脉移植物通畅率具有最强的证据支持。另一方面,静脉外部支撑的使用、内镜采集、静脉保存溶液和吻合术以及移植物构型需要进一步研究。我们还分析了治疗静脉移植物失败的策略:在可行的情况下,重新进行 CABG 和原生血管的主要经皮冠状动脉介入治疗 (PCI) 是最佳选择,其次是针对失败移植物的经皮介入治疗。