Nader Georgette, Yavari Majid, Timilsina Anisha, Rayamajhi Sumugdha
Internal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
Internal Medicine, Michigan State University-Sparrow Hospital, Lansing, USA.
Cureus. 2023 Dec 21;15(12):e50885. doi: 10.7759/cureus.50885. eCollection 2023 Dec.
Cutaneous small vessel leukocytoclastic vasculitis (LCV) is isolated to the dependent areas of the skin. LCV can be induced by pharmaceutical drugs, and management requires abrupt discontinuation of the offending drug. Warfarin is a rare medication to cause LCV, with sparse literature to date. Here, we present a case of warfarin-induced LCV, complicated by a patient's comorbid left ventricular thrombus, and successful treatment with discontinuation of warfarin and replacement with a direct oral anticoagulant (apixaban).
皮肤小血管白细胞破碎性血管炎(LCV)局限于皮肤的下垂部位。LCV可由药物诱发,治疗需要立即停用致病药物。华法林是一种罕见的可导致LCV的药物,迄今为止相关文献较少。在此,我们报告一例华法林诱发的LCV病例,该病例合并患者的左心室血栓形成,并通过停用华法林并用直接口服抗凝剂(阿哌沙班)替代进行成功治疗。