Liu Yun, Qin Kaijie, Zhu Jiaxi, Yao Haoyi, Wang Zhe, Zhou Mi, Ye Xiaofeng, Li Haiqing, Qiu Jiapei, Zhu Yunpeng, Zhao Qiang
Department of Cardiovascular Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
J Thorac Dis. 2023 Dec 30;15(12):6408-6418. doi: 10.21037/jtd-23-574. Epub 2023 Nov 23.
The actual patency rate of the radial artery (RA) grafts 1 week and 1 year after coronary artery bypass grafting (CABG) has not been extensively reported on. We used coronary computed tomography angiography (CCTA) to evaluate the patency rate of RA grafts and compared it with that of saphenous vein (SV) grafts.
In this observational cohort study, 80 patients who underwent urgent or elective CABG with RA and SV grafts at Ruijin Hospital from August 2019 to June 2021 were included. Follow-up CCTA scans were completed about 1 year postoperation in the out-patient clinic. We graded the grafts into four classes: A, excellent; B, graft diameter <50% of target coronary artery; O, occluded; and S, string sign. Both S and O were defined as graft failure.
The patients' mean age was 58.48±8.06 years, and 87.5% (70/80) of the patients were male. The 1-week patency rate of the left internal mammary artery (LIMA), RA, and SV grafts were 98.7% (75/76), 76.3% (61/80), and 93.8% (75/80), respectively. At 1 year, the patency rate of the LIMA, RA, and SV grafts were 97.4% (74/76), 80.0% (64/80), and 81.3% (65/80), respectively. The RA graft patency rate was lower than was the SV graft patency rate perioperatively [relative risk (RR): 0.918; 95% confidence interval (CI): 0.852-0.990; P=0.007]. Moreover, 63.6% (7/11) of RA grafts graded S and 25.0% (2/8) of RA grafts graded O were defined as patent (graded A or B) at 1 year postoperation. Compared with SV grafts, more RA grafts improved (RA: 12/80, 15.0%; SV: 0%) and fewer RA grafts deteriorated (RV: 10/80, 12.5%; SV: 19/80, 23.8%) from 1 week to 1 year (P=0.001). The patency rate of the 2 types of grafts became similar at 1 year postoperation (RR: 0.560; 95% CI: 0.113-2.781; P>0.99).
RA grafts had a lower patency rate than did SV grafts 1 week after operation. However, because of the "revival" phenomena and lower attrition rate, the patency rate of the two kinds of grafts did not show any significant difference at 1 year.
冠状动脉旁路移植术(CABG)后1周和1年时桡动脉(RA)移植物的实际通畅率尚未得到广泛报道。我们采用冠状动脉计算机断层扫描血管造影(CCTA)评估RA移植物的通畅率,并将其与大隐静脉(SV)移植物的通畅率进行比较。
在这项观察性队列研究中,纳入了2019年8月至2021年6月在瑞金医院接受紧急或择期CABG并使用RA和SV移植物的80例患者。术后约1年在门诊完成随访CCTA扫描。我们将移植物分为四类:A,优;B,移植物直径<目标冠状动脉的50%;O,闭塞;S,线样征。S和O均定义为移植物失败。
患者的平均年龄为58.48±8.06岁,87.5%(70/80)的患者为男性。左乳内动脉(LIMA)、RA和SV移植物的1周通畅率分别为98.7%(75/76), 76.3%(61/80)和93.8%(75/80)。1年时,LIMA、RA和SV移植物通畅率分别为97.4%(74/76), 80.0%(64/80)和81.3%(65/80)。围手术期RA移植物通畅率低于SV移植物通畅率[相对危险度(RR):0.918;95%置信区间(CI):0.852 - 0.990;P = 0.007]。此外,术后1年时,63.6%(7/11)分级为S的RA移植物和25.0%(2/8)分级为O的RA移植物被定义为通畅(分级为A或B)。与SV移植物相比,从1周到1年,更多的RA移植物情况改善(RA:12/80,15.0%;SV:0%),更少的RA移植物情况恶化(RV:10/80,12.5%;SV:19/80,23.8%)(P = 0.001)。术后1年时两种移植物的通畅率变得相似(RR:0.560;95% CI:0.113 - 2.781;P>0.99)。
术后1周时RA移植物的通畅率低于SV移植物。然而,由于“复苏”现象和较低的损耗率,两种移植物的通畅率在1年时未显示出任何显著差异。