Girotti Paolo Nicola Camillo, Bianchi Fabrizio
General, Visceral and Thoracic Surgery Department, Landeskrankenhaus Feldkirch, Feldkirch, Austria.
Unit of Cancer Biomarkers, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.
J Thorac Dis. 2023 Dec 30;15(12):7077-7087. doi: 10.21037/jtd-23-650. Epub 2023 Dec 26.
What is the best material in the case of prosthesis used to replace major chest wall resection is still unknown. We reviewed most significant literature focused on the type of prosthetic materials available by highlighting their relative pros and cons.
We reviewed most significant articles, including clinical results of relevant case series (retrospective studies), published in English in the last 23 years: PubMed, Embase and Scopus databases were used in our search in the period between the 1 January 1999 and 31 December 2022.
Overall, our literature review revealed lack of uniformity or conformity in the surgical strategies described for chest wall reconstruction with no internationally accepted standard in terms of decisions and optimal prosthetic materials and type of prostheses (soft, rigid, biological). Despite the increased interest in chest wall reconstruction, we observed a general lack of substantial prospective and multicentric studies. Likewise, there are not substantial data which may guide to the choice of optimal prosthetics in terms of characteristics and biocompatibility.
A variety of materials are available for reconstruction, including synthetic and biological meshes, flexible and rigid patches, and metal osteosynthesis systems. The material chosen should be optimized to each patient and damaged tissues to be restored. Prospective and multicentric studies are necessary to address current limits in this surgical field.
在用于替代大面积胸壁切除的假体案例中,最佳材料仍不明确。我们回顾了最重要的文献,重点介绍了可用的假体材料类型,并突出了它们各自的优缺点。
我们回顾了过去23年以英文发表的最重要文章,包括相关病例系列(回顾性研究)的临床结果:我们在1999年1月1日至2022年12月31日期间使用PubMed、Embase和Scopus数据库进行检索。
总体而言,我们的文献综述显示,在胸壁重建的手术策略描述中缺乏一致性或规范性,在决策、最佳假体材料和假体类型(软性、硬性、生物性)方面没有国际公认的标准。尽管对胸壁重建的兴趣有所增加,但我们观察到普遍缺乏大量的前瞻性和多中心研究。同样,在假体的特性和生物相容性方面,也没有足够的数据来指导最佳假体的选择。
有多种材料可用于重建,包括合成和生物网片、柔性和刚性补片以及金属骨固定系统。所选材料应根据每个患者和待修复的受损组织进行优化。前瞻性和多中心研究对于解决该手术领域当前的局限性是必要的。