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神经矫形评估和管理在意识障碍延长的患者:综述。

Neuro-orthopaedic assessment and management in patients with prolonged disorders of consciousness: A review.

机构信息

Coma Science Group, GIGA-Consciousness, University of Liege, Liege, Belgium.

Centre du Cerveau, University Hospital of Liege, Liege, Belgium.

出版信息

NeuroRehabilitation. 2024;54(1):75-90. doi: 10.3233/NRE-230137.

Abstract

BACKGROUND

Following a severe acquired brain injury, neuro-orthopaedic disorders are commonplace. While these disorders can impact patients' functional recovery and quality of life, little is known regarding the assessment, management and treatment of neuro-orthopaedic disorders in patients with disorders of consciousness (DoC).

OBJECTIVE

To describe neuro-orthopaedic disorders in the context of DoC and provide insights on their management and treatment.

METHODS

A review of the literature was conducted focusing on neuro-orthopaedic disorders in patients with prolonged DoC.

RESULTS

Few studies have investigated the prevalence of spastic paresis in patients with prolonged DoC, which is extremely high, as well as its correlation with pain. Pilot studies exploring the effects of pharmacological treatments and physical therapy show encouraging results yet have limited efficacy. Other neuro-orthopaedic disorders, such as heterotopic ossification, are still poorly investigated.

CONCLUSION

The literature of neuro-orthopaedic disorders in patients with prolonged DoC remains scarce, mainly focusing on spastic paresis. We recommend treating neuro-orthopaedic disorders in their early phases to prevent complications such as pain and improve patients' recovery. Additionally, this approach could enhance patients' ability to behaviourally demonstrate signs of consciousness, especially in the context of covert awareness.

摘要

背景

在严重的后天性脑损伤后,神经矫形疾病很常见。虽然这些疾病会影响患者的功能恢复和生活质量,但对于意识障碍(DOC)患者的神经矫形疾病的评估、管理和治疗知之甚少。

目的

描述意识障碍患者中的神经矫形疾病,并提供对其管理和治疗的见解。

方法

对文献进行了回顾,重点是长期意识障碍患者的神经矫形疾病。

结果

很少有研究调查过长时间意识障碍患者痉挛性麻痹的患病率,其患病率极高,且与疼痛相关。探索药物治疗和物理治疗效果的初步研究结果令人鼓舞,但疗效有限。其他神经矫形疾病,如异位骨化,仍研究不足。

结论

关于长期意识障碍患者神经矫形疾病的文献仍然很少,主要集中在痉挛性麻痹上。我们建议在早期治疗神经矫形疾病,以预防疼痛等并发症,并改善患者的恢复。此外,这种方法可以增强患者表现出意识迹象的能力,特别是在隐匿意识的情况下。

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