Weckner W, Kühler E, Bellmann K P, Stade M
Zentralbl Chir. 1986;111(23):1460-8.
Evaluation of 135 post-mortem reports over a period from 1953 to 1985 showed that 107 patients without adequate therapy for peritonitis had died of gallbladder perforation within 32 hours from surgery. Another 28 had died of gallbladder perforation following cholecystectomy. Forty patients had been hospitalised in moribund condition and died within 24 hours from admission. Three patients died of the consequences of undetected postoperative or posttraumatic cholecystitis, while another five died following appendectomy or herniotomy, after destructive cholecystitis in them had escaped detection. Cholecystectomy was performed on 28 patients for perforated destructive cholecystitis, and 25 of these died of peritonitis within 32 hours. Bronchopneumonia was the major cause of death of two patients and purulent cholangitis in a third case. Once early operation for acute cholecystitis had been introduced in 1965, no single patient was recordable from the post-mortem documentation who had died of the sequels of untreated gallbladder perforation below the age of 60.
对1953年至1985年期间135份尸检报告的评估显示,107例未接受充分腹膜炎治疗的患者在手术后32小时内因胆囊穿孔死亡。另外28例在胆囊切除术后因胆囊穿孔死亡。40例患者入院时病情垂危,入院后24小时内死亡。3例患者死于未被发现的术后或创伤后胆囊炎的后果,另有5例在阑尾切除术或疝修补术后死亡,此前他们的坏疽性胆囊炎未被发现。28例患者因穿孔性坏疽性胆囊炎接受了胆囊切除术,其中25例在32小时内因腹膜炎死亡。支气管肺炎是2例患者的主要死因,第3例患者的主要死因是化脓性胆管炎。自1965年引入急性胆囊炎早期手术以来,尸检记录中没有60岁以下患者死于未经治疗的胆囊穿孔后遗症的病例。