Campion D R, McCusker R H, Richardson R L
Acta Anat (Basel). 1987;128(1):67-70. doi: 10.1159/000146317.
Female Wistar-Furth rats were injected at one week of age with cells from either the GH1 or GH3 rat pituitary cell lines. Controls were injected with vehicle. Rats were killed at 11 weeks of age and satellite cells in the soleus and extensor digitorum longus (EDL) muscles were examined using transmission electron microscopy. Satellite cells in both the soleus and EDL muscles of rats with tumours which secreted growth hormone generally appeared to be metabolically more active than those cells seen in the muscles of control rats. The source of pituitary cell line did not appear to influence satellite cell ultrastructure. In rare instances, myofibers of tumor-bearing rats appeared to extend cytoplasmic projections around satellite cells as if to engulf the latter. There was no evidence of a pathological condition. Since only one time frame was observed, the effects of prolonged exposure to elevated blood growth hormone levels on satellite cells are not known.
将一周龄的雌性Wistar-Furth大鼠注射来自GH1或GH3大鼠垂体细胞系的细胞。对照组注射赋形剂。大鼠在11周龄时处死，使用透射电子显微镜检查比目鱼肌和趾长伸肌（EDL）中的卫星细胞。分泌生长激素的肿瘤大鼠的比目鱼肌和EDL肌中的卫星细胞通常在代谢上似乎比对照大鼠肌肉中的那些细胞更活跃。垂体细胞系的来源似乎不影响卫星细胞超微结构。在极少数情况下，荷瘤大鼠的肌纤维似乎在卫星细胞周围延伸细胞质突起，好像要吞噬卫星细胞。没有病理状况的证据。由于只观察了一个时间框架，因此长期暴露于升高的血液生长激素水平对卫星细胞的影响尚不清楚。
