Aquilonius S M, Hartvig P
Acta Neurol Scand. 1986 Nov;74(5):379-82. doi: 10.1111/j.1600-0404.1986.tb03529.x.
This report is based on the use of L-dopa-containing drugs within 24 Swedish counties in the period 1977-1984. The mean utilization of these drugs in Sweden in 1984 was 1.46 defined daily doses (DDD)/day X 10(3) inhabitants (inh). As Parkinson's disease is virtually the only condition for which these drugs are prescribed, it seems highly probable that the determining factor for their use today is the prevalence of the disease. The exceptionally high utilization (2.34 DDD/day X 10(3) inh) of L-dopa-containing drugs in the county of Gävleborg, warranted further analyses of subareas in this particular county. The use is discussed in relation to environmental factors.
本报告基于1977 - 1984年期间瑞典24个郡内含左旋多巴药物的使用情况。1984年这些药物在瑞典的平均使用量为1.46限定日剂量(DDD)/天×10³居民(inh)。由于帕金森病几乎是这些药物唯一的处方用药病症,那么目前其使用的决定性因素很可能就是该疾病的患病率。耶夫勒堡郡含左旋多巴药物的异常高使用量(2.34 DDD/天×10³ inh),促使对该特定郡的分区进行进一步分析。文中结合环境因素对使用情况进行了讨论。