Škrgat Sabina, Harlander Matevž, Janić Miodrag
Department of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, SI-1000 Ljubljana, Slovenia.
Medical Faculty, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Biomedicines. 2024 Jan 12;12(1):173. doi: 10.3390/biomedicines12010173.
Common inflammatory ground links obesity, insulin resistance, and asthma. As recognition of their interplay, one worsening the natural course of the other, is recognised, questions remain about how to adequately address them altogether to improve clinical outcomes. The present manuscript sheds light on the problem, describing possible pathophysiological links, clinical views, and therapeutic challenges, raising questions about what remains to be done, and calling for multidisciplinary treatment of these patients to detect diseases early and adequately address them before they become full-blown and deteriorate their health and quality of life.
常见的炎症基础将肥胖、胰岛素抵抗和哮喘联系在一起。随着人们认识到它们之间的相互作用，即一种情况会使另一种情况的自然病程恶化，关于如何全面充分地应对这些情况以改善临床结果的问题仍然存在。本手稿阐明了这一问题，描述了可能的病理生理联系、临床观点和治疗挑战，提出了仍有待完成的工作的问题，并呼吁对这些患者进行多学科治疗，以便早期发现疾病并在疾病全面爆发并损害他们的健康和生活质量之前充分应对。
