Lauritzen A F, Kvist E, Bredesen J, Luke M
Acta Pathol Microbiol Immunol Scand A. 1987 Jan;95(1):7-10. doi: 10.1111/j.1699-0463.1987.tb00002_95a.x.
Thirty-seven patients with upper urinary tract tumours were evaluated for grade, stage, histological type, location, presence or absence of vascular invasion, abnormalities in the urothelium adjacent to the tumours, tumour multiplicity and patient survival. A good correlation between tumour grade and stage was found in the transitional cell tumours. Squamous cell carcinomas and adenocarcinomas were high-stage tumours. Vascular invasion was present in most high-grade tumours, squamous cell carcinoma and adenocarcinomas. Four patients had multifocal tumours of both pelvis and ureter. Three developed ureteric stump carcinomas and 13 had further development of bladder carcinomas. The cumulative 5 and 10 year survival rates were 43 and 23% respectively.
对37例上尿路肿瘤患者进行了分级、分期、组织学类型、位置、有无血管侵犯、肿瘤邻近尿路上皮异常、肿瘤多发性及患者生存率的评估。在移行细胞肿瘤中发现肿瘤分级与分期之间有良好的相关性。鳞状细胞癌和腺癌为高分期肿瘤。大多数高级别肿瘤、鳞状细胞癌和腺癌存在血管侵犯。4例患者骨盆和输尿管均有多灶性肿瘤。3例发生输尿管残端癌,13例膀胱癌进一步发展。累积5年和10年生存率分别为43%和23%。