Vojnits Kinga, Mohseni Majid, Parvinzadeh Gashti Mazeyar, Nadaraja Anupama Vijaya, Karimianghadim Ramin, Crowther Ben, Field Brad, Golovin Kevin, Pakpour Sepideh
School of Engineering, University of British Columbia, Kelowna, BC V6T 1Z2, Canada.
Research and Development Laboratory, PRE Labs, Inc., Kelowna, BC V1X 7Y5, Canada.
Materials (Basel). 2024 Jan 12;17(2):383. doi: 10.3390/ma17020383.
Antibiotic-resistant bacteria, ESKAPE pathogens, present a significant and alarming threat to public health and healthcare systems. This study addresses the urgent need to combat antimicrobial resistance by exploring alternative ways to reduce the health and cost implications of infections caused by these pathogens. To disrupt their transmission, integrating antimicrobial textiles into personal protective equipment (PPE) is an encouraging avenue. Nevertheless, ensuring the effectiveness and safety of these textiles remains a persistent challenge. To achieve this, we conduct a comprehensive study that systematically compares the effectiveness and potential toxicity of five commonly used antimicrobial agents. To guide decision making, a MULTIMOORA method is employed to select and rank the optimal antimicrobial textile finishes. Through this approach, we determine that silver nitrate is the most suitable choice, while a methoxy-terminated quaternary ammonium compound is deemed less favorable in meeting the desired criteria. The findings of this study offer valuable insights and guidelines for the development of antimicrobial textiles that effectively address the requirements of effectiveness, safety, and durability. Implementing these research outcomes within the textile industry can significantly enhance protection against microbial infections, contribute to the improvement of public health, and mitigate the spread of infectious diseases.
抗生素耐药细菌,即ESKAPE病原体,对公共卫生和医疗保健系统构成了重大且令人担忧的威胁。本研究通过探索替代方法来减少这些病原体引起的感染对健康和成本的影响,以应对抗菌耐药性这一紧迫需求。为了阻断它们的传播,将抗菌纺织品整合到个人防护装备(PPE)中是一条令人鼓舞的途径。然而,确保这些纺织品的有效性和安全性仍然是一个持续存在的挑战。为了实现这一目标,我们进行了一项全面的研究,系统地比较了五种常用抗菌剂的有效性和潜在毒性。为了指导决策,采用了MULTIMOORA方法来选择和排名最佳的抗菌纺织品整理剂。通过这种方法,我们确定硝酸银是最合适的选择,而甲氧基封端的季铵化合物在满足所需标准方面被认为不太理想。本研究的结果为开发能有效满足有效性、安全性和耐用性要求的抗菌纺织品提供了有价值的见解和指导方针。在纺织行业内实施这些研究成果可以显著增强对微生物感染的防护,有助于改善公共卫生,并减轻传染病的传播。