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在手术后加速康复方案背景下的泌尿外科腹腔镜或机器人手术镇痛策略:一项比较竖脊肌平面阻滞与腹横肌平面阻滞的前瞻性研究

Analgesic Strategies for Urologic Videolaparoscopic or Robotic Surgery in the Context of an Enhanced Recovery after Surgery Protocol: A Prospective Study Comparing Erector Spinae Plane Block versus Transversus Abdominis Plane Block.

作者信息

Micali Marco, Cucciolini Giada, Bertoni Giulia, Gandini Michela, Lattuada Marco, Santori Gregorio, Introini Carlo, Corradi Francesco, Brusasco Claudia

机构信息

Anaesthesia and Intensive Care Unit, E.O. Ospedali Galliera, 16128 Genoa, Italy.

Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy.

出版信息

J Clin Med. 2024 Jan 10;13(2):383. doi: 10.3390/jcm13020383.

Abstract

Regional anesthesia in postoperative pain management has developed in recent years, especially with the advent of fascial plane blocks. This study aims to compare the ultrasound-guided bilateral erector spinae plane block (ESPB) versus the ultrasound-guided bilateral transversus abdominis plane block (TAPB) on postoperative analgesia after laparoscopic or robotic urologic surgery. This was a prospective observational study; 97 patients (ESPB-group) received bilateral ultrasound-guided ESPB with 20 mL of ropivacaine 0.375% plus 0.5 mcg/kg of dexmedetomidine in each side at the level of T7-T9 and 93 patients (TAPB-group) received bilateral ultrasound-guided TAPB with 20 mL ropivacaine 0.375% or 0.25%. The primary outcome was the postoperative numeric rating scale (NRS) pain score, which was significantly lower in the ESPB group on postoperative days 0, 1, 2, and 3 ( < 0.001) and, consequently, the number of patients requiring postoperative supplemental analgesic rescue therapies was significantly lower ( < 0.001). Concerning the secondary outcomes, consumption of ropivacaine was significantly lower in the group ( < 0.001) and the total amount of analgesic rescue doses was significantly lower in the ESPB-group than the TAPB-group in postoperative days from 2 to 4 (1 vs. 3, > 0.001). Incidence of postoperative nausea and vomiting was higher in the TAPB group and no block-related complications were observed. Our data indicate that ESPB provides postoperative pain control at least as good as TAPB plus morphine, with less local anesthetic needed.

摘要

近年来,区域麻醉在术后疼痛管理中得到了发展,尤其是随着筋膜平面阻滞的出现。本研究旨在比较超声引导下双侧竖脊肌平面阻滞(ESPB)与超声引导下双侧腹横肌平面阻滞(TAPB)对腹腔镜或机器人泌尿外科手术后的术后镇痛效果。这是一项前瞻性观察研究;97例患者(ESPB组)在T7-T9水平接受双侧超声引导下的ESPB,每侧注射20 mL 0.375%的罗哌卡因加0.5 mcg/kg的右美托咪定,93例患者(TAPB组)接受双侧超声引导下的TAPB,注射20 mL 0.375%或0.25%的罗哌卡因。主要结局是术后数字评分量表(NRS)疼痛评分,ESPB组在术后第0、1、2和3天的疼痛评分显著更低(<0.001),因此,需要术后补充镇痛解救治疗的患者数量显著更少(<0.001)。关于次要结局,罗哌卡因的消耗量在ESPB组显著更低(<0.001),在术后第2至4天,ESPB组的镇痛解救剂量总量显著低于TAPB组(1 vs. 3,>0.001)。TAPB组术后恶心呕吐的发生率更高,未观察到与阻滞相关的并发症。我们的数据表明,ESPB提供的术后疼痛控制至少与TAPB加吗啡一样好,且所需局部麻醉剂更少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30bf/10816131/07b519a240db/jcm-13-00383-g001.jpg

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